4-Amino-2,3-difluorobenzonitrile
Artikel-Nr:
(BOSSBS-11988R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11988R-A555
Lokale Artikelnummer::
BOSSBS-11988R-A555
Beschreibung:
Brain-specific neurabin I (neural tissue-specific F-actin binding protein I) is highly concentrated in the synapse of developed neurons; it localizes in the growth cone lamellipodia during neuronal development (1). Suppression of endogenous neurabin in rat hippocampal neurons inhibits neurite formation (1). Neurabin I recruits active PP1 via a PP1-docking sequence; mutation of the PP1-binding motif halts filopodia and restores stress fibers in neurabin I-expressing cells (2,3). Neurabin II (Spinophilin) is ubiquitously expressed but is abundantly expressed in brain (4). Neurabin II localizes to neuronal dentritic spines, which are the specialized protrusions from dendritic shafts that receive most of the excitatory input in the CNS (5). Neurabin II may regulate dendritic spine properties as neurabin II(-) mice have increased spine density during development in vitro and exhibit altered filopodial formation in cultured cells (5). Neurabin may also play a role in glutamatergic transmission as Neurabin II(-) mice exhibit reduced long-term depression and resistance to kainate-induced seizures and neronal apoptosis (5). Neurabin II complexes with the catalytic subunit of protein phosphatase-1 (PP1) in vitro thus modulating the activity of PP1 (4).
VE:
1 * 100 µl
Artikel-Nr:
(1337809.)
Lieferant:
USP
Hersteller-Artikelnummer::
1337809
Lokale Artikelnummer::
USPH1337809
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 100 mg
Artikel-Nr:
(1680018.)
Lieferant:
USP
Hersteller-Artikelnummer::
1680018
Lokale Artikelnummer::
USPH1680018
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 50 mg
Lieferant:
Sigma-Aldrich
Beschreibung:
Indan, Sigma-Aldrich®
Artikel-Nr:
(217-9125)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
246240604
Lokale Artikelnummer::
SCOT246240604
Beschreibung:
These stoppers are made from SBW glass and have an octagonal head for good grip.
VE:
1 * 1 ST
Lieferant:
Thermo Scientific
Beschreibung:
di-Natrium-L(+)-tartrat Dihydrat 99+% ACS
Artikel-Nr:
(612-2794)
Lieferant:
HIRSCHMANN
Hersteller-Artikelnummer::
6500183
Lokale Artikelnummer::
HIRS6500183
Beschreibung:
Sauerstoffflaschen nach Winkler, mit weißem Beschriftungsschild.
VE:
1 * 1 ST
Lieferant:
Agilent
Beschreibung:
Spritzen, Chromatographie, Autosampler syringes, Fixed needle, Volumen: 5 µl, Spitzentyp: Cone, Gauge: 23, Länge: 50 mm, Für: CTC CombiPAL, GC PAL, VE: 1
Lieferant:
MP Biomedicals
Beschreibung:
Colorless, clear solution at 10 g + 100 ml, in water (Lit.).
Artikel-Nr:
(SIAL162108-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
162108-5G
Lokale Artikelnummer::
SIAL162108-5G
Beschreibung:
4-Aminoindan, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
Sigma-Aldrich
Beschreibung:
5-Brom-1-indanon, Sigma-Aldrich®
Lieferant:
EDQM
Beschreibung:
Organic Standard, Ofloxacin impurity A, (3RS)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid (FPA)
Artikel-Nr:
(SIAL10784-100G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
10784-100G
Lokale Artikelnummer::
SIAL10784-100G
Beschreibung:
Phenazon, Sigma-Aldrich®
VE:
1 * 100 g
Artikel-Nr:
(FLUO023006-1G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
023006-1G
Lokale Artikelnummer::
FLUO023006-1G
Beschreibung:
Ethyl-3,4-ethylendioxybenzoylformiat
VE:
1 * 1 g
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Artikel-Nr:
(BIBB443038N)
Lieferant:
SciLabware
Hersteller-Artikelnummer::
443038N
Lokale Artikelnummer::
BIBB443038N
Beschreibung:
PYREX®, borosilicate glass, with NS-PE stopper.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-13492R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13492R-A647
Lokale Artikelnummer::
BOSSBS-13492R-A647
Beschreibung:
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
VE:
1 * 100 µl
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