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N1-Methylbenzene-1,2-diamine+dihydrochloride
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N1-Methylbenzene-1,2-diamine+dihydrochloride
Artikel-Nr:
(PRSI33-656)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-656
Lokale Artikelnummer::
PRSI33-656
Beschreibung:
Recognises a protein of 165 kDa, identified as Desmoglein-2 (DSG2). This monoclonal antibody Recognises the extracellular domain of human desmoglein-2. Desmoglein-2 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cytoplasmic region containing five desmoglein repeat domains which share homology with the cadherin repeats. Instead of having the HAV adhesion motif found in type I cadherins, desmogleins have R/YAL as the adhesion motif on its amino-terminal cadherin repeat. The cytoplasmic tails of desmogleins interact with desmoplakins, plakoglobin and plakophilins. In turn, these proteins link the desmogleins with the intermediate filaments. Desmoglein-2 has been shown to be important in establishing cell-cell adhesion and function in epithelial cells. Desmoglein2 was originally identified in colon carcinoma and colon, and was named HDGC (human desmoglein colon).
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI33-655)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-655
Lokale Artikelnummer::
PRSI33-655
Beschreibung:
Recognises a protein of 165 kDa, identified as Desmoglein-2 (DSG2). This monoclonal antibody Recognises the extracellular domain of human desmoglein-2. Desmoglein-2 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Human Desmoglein-2 is a type I transmembrane glycoprotein of 1117 amino acid (aa) residues with a 23 aa signal peptide and a 25 aa propeptide. It differs from other classic cadherins by having four instead of five cadherin repeat domains in its extracellular region, and a much larger cytoplasmic region containing five desmoglein repeat domains which share homology with the cadherin repeats. Instead of having the HAV adhesion motif found in type I cadherins, desmogleins have R/YAL as the adhesion motif on its amino-terminal cadherin repeat. The cytoplasmic tails of desmogleins interact with desmoplakins, plakoglobin and plakophilins. In turn, these proteins link the desmogleins with the intermediate filaments. Desmoglein-2 has been shown to be important in establishing cell-cell adhesion and function in epithelial cells. Desmoglein2 was originally identified in colon carcinoma and colon, and was named HDGC (human desmoglein colon).
VE:
1 * 100 µG
New Product
Artikel-Nr:
(MOLE54799339-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
54799339-1KG
Lokale Artikelnummer::
MOLE54799339-1KG
Beschreibung:
EDTA Tetranatriumsalz Dihydrat
VE:
1 * 1 kg
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(MOLEM70678137)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M70678137
Lokale Artikelnummer::
MOLEM70678137
Beschreibung:
EDTA Tetranatriumsalz Dihydrat
VE:
1 * 100 g
This is a MarketSource item. Additional charges may apply
Lieferant:
Alfa Aesar
Beschreibung:
EDTA Tetranatriumsalz Dihydrat 99-101%, ultrarein
Lieferant:
Sigma-Aldrich
Beschreibung:
EDTA Tetranatriumsalz Dihydrat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
EDTA Tetranatriumsalz Dihydrat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
EDTA Tetranatriumsalz Dihydrat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
EDTA Tetranatriumsalz Dihydrat, Sigma-Aldrich®
Artikel-Nr:
(PRSI25-765)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-765
Lokale Artikelnummer::
PRSI25-765
Beschreibung:
CLEC4M is a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
VE:
1 * 50 µG
Lieferant:
Sigma-Aldrich
Beschreibung:
2,3-Butandionmonoxim, Supelco®
Artikel-Nr:
(8.41655.0100)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.41655.0100
Lokale Artikelnummer::
MERC8.41655.0100
Beschreibung:
2,3-Dichloranisol
VE:
1 * 100 g
Lieferant:
Merck
Beschreibung:
2,3-Hexandion zur Synthese, Sigma-Aldrich®
Artikel-Nr:
(39760-10ML)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
39760-10ML
Lokale Artikelnummer::
SUPL39760-10ML
Beschreibung:
2,3-Dimethylbutan, Supelco®
VE:
1 * 10 mL
Artikel-Nr:
(8.20418.0100)
Lieferant:
Merck
Hersteller-Artikelnummer::
8.20418.0100
Lokale Artikelnummer::
MERC8.20418.0100
Beschreibung:
(±)-Ethyl-2,3-dibrompropionat
VE:
1 * 100 mL
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Naphthalin-2,3-dicarbonitril, Sigma-Aldrich®
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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