5-Bromo-2-fluoro-3-(trifluoromethyl)benzoic+acid
Artikel-Nr:
(BOSSBS-6675R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6675R-HRP
Lokale Artikelnummer::
BOSSBS-6675R-HRP
Beschreibung:
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6675R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6675R-A647
Lokale Artikelnummer::
BOSSBS-6675R-A647
Beschreibung:
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13028R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13028R-A555
Lokale Artikelnummer::
BOSSBS-13028R-A555
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13028R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13028R-A680
Lokale Artikelnummer::
BOSSBS-13028R-A680
Beschreibung:
Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. DPP10 (dipeptidyl-peptidase 10), also known as DPRP3 (dipeptidyl peptidase IV-related protein 3), DPL2 or DPPY, is a non-functional dipeptidyl peptidase which can bind to the potassium channels KV4.1 and KV4.2. It is a single-pass type II membrane protein expressed in spinal cord, adrenal glands, pancreas and brain tissues and may act as a modulator for cell surface expression and activity of KV4.1 and KV4.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0236R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0236R-CY5
Lokale Artikelnummer::
BOSSBS-0236R-CY5
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12179R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12179R-HRP
Lokale Artikelnummer::
BOSSBS-12179R-HRP
Beschreibung:
The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5356R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5356R-HRP
Lokale Artikelnummer::
BOSSBS-5356R-HRP
Beschreibung:
Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9443R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9443R
Lokale Artikelnummer::
BOSSBS-9443R
Beschreibung:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1289R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1289R-A680
Lokale Artikelnummer::
BOSSBS-1289R-A680
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1289R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1289R-A350
Lokale Artikelnummer::
BOSSBS-1289R-A350
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1289R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1289R-A488
Lokale Artikelnummer::
BOSSBS-1289R-A488
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD129758-500G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD129758-500G
Lokale Artikelnummer::
BLDPBD129758-500G
Beschreibung:
EDTA Trikaliumsalz 98+%
VE:
1 * 500 g
Artikel-Nr:
(BOSSBS-6675R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6675R-CY3
Lokale Artikelnummer::
BOSSBS-6675R-CY3
Beschreibung:
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6675R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6675R-CY5
Lokale Artikelnummer::
BOSSBS-6675R-CY5
Beschreibung:
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0236R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0236R-CY7
Lokale Artikelnummer::
BOSSBS-0236R-CY7
Beschreibung:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
VE:
1 * 100 µl
Lieferant:
CHEMPUR
Beschreibung:
2,4,5-Trifluorbenzoylchlorid
Preis auf Anfrage
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