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Tetrachlorphthalsäureanhydrid
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Tetrachlorphthalsäureanhydrid
Artikel-Nr:
(BOSSBS-0572R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0572R-A350
Lokale Artikelnummer::
BOSSBS-0572R-A350
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6674R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6674R-A555
Lokale Artikelnummer::
BOSSBS-6674R-A555
Beschreibung:
KCNK3 encodes one of the members of the superfamily of potassium channel proteins containing two pore forming P domains. The gene product is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2162R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2162R-HRP
Lokale Artikelnummer::
BOSSBS-2162R-HRP
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5955R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5955R-FITC
Lokale Artikelnummer::
BOSSBS-5955R-FITC
Beschreibung:
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0216R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0216R-A647
Lokale Artikelnummer::
BOSSBS-0216R-A647
Beschreibung:
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2510R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2510R-HRP
Lokale Artikelnummer::
BOSSBS-2510R-HRP
Beschreibung:
ZNF217 (Zinc-finger protein 217) is a Kruppel-like zinc-finger protein which functions as a transcriptional repressor protein and forms a complex with a number of proteins including CoREST, BHC110/LSD1, HDAC2 and CtBP1. ZNF217 has been shown to repress E-cadherin promoter activity. ZNF217 is overexpressed in a number of cancers including breast and ovarian. ZNF217 and its associated proteins have been implicated in a novel pathway that is involved in cancer progression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4846R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4846R-HRP
Lokale Artikelnummer::
BOSSBS-4846R-HRP
Beschreibung:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3152R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3152R-CY5
Lokale Artikelnummer::
BOSSBS-3152R-CY5
Beschreibung:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0205R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0205R-A350
Lokale Artikelnummer::
BOSSBS-0205R-A350
Beschreibung:
GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13254R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13254R-A488
Lokale Artikelnummer::
BOSSBS-13254R-A488
Beschreibung:
This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3299R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3299R-CY5.5
Lokale Artikelnummer::
BOSSBS-3299R-CY5.5
Beschreibung:
E3 ubiquitin-protein ligase accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. This protein inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. Furthermore, it promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5, and promotes the ubiquitination and degradation of SGK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13254R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13254R-FITC
Lokale Artikelnummer::
BOSSBS-13254R-FITC
Beschreibung:
This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4110R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4110R-CY5
Lokale Artikelnummer::
BOSSBS-4110R-CY5
Beschreibung:
GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes. Involved in the regulation of cytokinesis; the function may involve SDCCAG3 and PTPN13 (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15561R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15561R-FITC
Lokale Artikelnummer::
BOSSBS-15561R-FITC
Beschreibung:
IFT20 is a gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components. This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13263R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13263R-CY3
Lokale Artikelnummer::
BOSSBS-13263R-CY3
Beschreibung:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma aminobutyric acid from L glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin dependent diabetes. This gene may also play a role in the stiff man syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7767R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7767R-CY5.5
Lokale Artikelnummer::
BOSSBS-7767R-CY5.5
Beschreibung:
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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