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(2-Hydroxylpropyl)-\u03B1-cyclodextrin
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(2-Hydroxylpropyl)-\u03B1-cyclodextrin
Artikel-Nr:
(BOSSBS-12054R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12054R-CY3
Lokale Artikelnummer::
BOSSBS-12054R-CY3
Beschreibung:
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9629R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9629R-CY7
Lokale Artikelnummer::
BOSSBS-9629R-CY7
Beschreibung:
Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9629R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9629R-CY5
Lokale Artikelnummer::
BOSSBS-9629R-CY5
Beschreibung:
Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5220R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5220R-A350
Lokale Artikelnummer::
BOSSBS-5220R-A350
Beschreibung:
BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants (alpha and beta) produced by alternate splicing, differ in their C-terminal ends. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1). It can form homodimers, and heterodimers with BAX, BAD, BAK and BclX(L). Heterodimerization with BAX requires intact BH1 and BH2 domains, and is necessary for anti-apoptotic activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11795R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11795R-CY3
Lokale Artikelnummer::
BOSSBS-11795R-CY3
Beschreibung:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11795R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11795R-CY5
Lokale Artikelnummer::
BOSSBS-11795R-CY5
Beschreibung:
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.
VE:
1 * 100 µl
Artikel-Nr:
(BSENS-080-100)
Lieferant:
Biosensis
Hersteller-Artikelnummer::
S-080-100
Lokale Artikelnummer::
BSENS-080-100
Beschreibung:
Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released. This antibody is raised in sheep to detect the prodomain of NGF not the mature peptide.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI6765)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6765
Lokale Artikelnummer::
PRSI6765
Beschreibung:
SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-10433R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10433R-HRP
Lokale Artikelnummer::
BOSSBS-10433R-HRP
Beschreibung:
Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6938R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6938R-A350
Lokale Artikelnummer::
BOSSBS-6938R-A350
Beschreibung:
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12054R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12054R-A647
Lokale Artikelnummer::
BOSSBS-12054R-A647
Beschreibung:
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10433R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10433R-FITC
Lokale Artikelnummer::
BOSSBS-10433R-FITC
Beschreibung:
Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13249R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13249R-A647
Lokale Artikelnummer::
BOSSBS-13249R-A647
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13249R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13249R-A555
Lokale Artikelnummer::
BOSSBS-13249R-A555
Beschreibung:
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12054R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12054R-FITC
Lokale Artikelnummer::
BOSSBS-12054R-FITC
Beschreibung:
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1641R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1641R-HRP
Lokale Artikelnummer::
BOSSBS-1641R-HRP
Beschreibung:
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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