COMBI-BLOCKS
Artikel-Nr:
(PRSI60-923)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-923
Lokale Artikelnummer::
PRSI60-923
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI30-210)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-210
Lokale Artikelnummer::
PRSI30-210
Beschreibung:
LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI30-046)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-046
Lokale Artikelnummer::
PRSI30-046
Beschreibung:
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI26-891)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-891
Lokale Artikelnummer::
PRSI26-891
Beschreibung:
AMN1 belongs to the AMN1 family. The exact function of AMN1 remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-963)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-963
Lokale Artikelnummer::
PRSI28-963
Beschreibung:
SOX15 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins.This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI60-641)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-641
Lokale Artikelnummer::
PRSI60-641
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI6779P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6779P
Lokale Artikelnummer::
PRSI6779P
Beschreibung:
YPEL5 peptide is used for blocking the activity of YPEL5 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI33-463)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
33-463
Lokale Artikelnummer::
PRSI33-463
Beschreibung:
CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterised.
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI27-702)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-702
Lokale Artikelnummer::
PRSI27-702
Beschreibung:
MXD4 is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-665)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-665
Lokale Artikelnummer::
PRSI92-665
Beschreibung:
Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function, location, and/or half-life. Small ubiquitin-like modifiers include SUMO1, SUMO2, SUMO3, and SUMO4. Except for SUMO4, all other SUMOs are ubiquitously expressed, including in the brain. In human, SUMO2 and SUMO3 are two highly homologous proteins, collectively called SUMO2/3. Several studies suggest that SUMO3 are associated with pathogenesis in several neurological diseases, including Alzheimer's disease, Parkinson's disease, and cerebral ischemia/stroke.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI29-301)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-301
Lokale Artikelnummer::
PRSI29-301
Beschreibung:
RPN1 is a type I integral membrane protein found only in the rough endoplasmic reticulum. It is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. RPN1 forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI30-718)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
30-718
Lokale Artikelnummer::
PRSI30-718
Beschreibung:
CACYBP is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin.The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI27-839)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-839
Lokale Artikelnummer::
PRSI27-839
Beschreibung:
SATB1 binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. SATB1 was thought to recognize the sugar-phosphate structure of double-stranded DNA.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI3761P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
3761P
Lokale Artikelnummer::
PRSI3761P
Beschreibung:
LSD1 peptide is used for blocking the activity of LSD1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5947P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5947P
Lokale Artikelnummer::
PRSI5947P
Beschreibung:
NOD1 peptide is used for blocking the activity of NOD1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-276)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-276
Lokale Artikelnummer::
PRSI79-276
Beschreibung:
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
VE:
1 * 100 µG
Preis auf Anfrage
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