Bis(2-methoxyethyl)amin
Artikel-Nr:
(PRSI92-701)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-701
Lokale Artikelnummer::
PRSI92-701
Beschreibung:
Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor- alpha and - beta . These two receptor isoforms dimerise upon binding the PDGF dimer, leading to three possible receptor combinations, namely - alpha alpha, - beta beta and - alpha beta . PDGFR alpha and PDGFR beta are members of the class III RTK family. Inappropriate PDGFR alpha and PDGFR beta signalling has been linked to a number of proliferative disorders.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI54-328)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
54-328
Lokale Artikelnummer::
PRSI54-328
Beschreibung:
Anti-GNB3 Rabbit Monoclonal Antibody [clone: D7]
VE:
1 * 100 µG
New Product
Artikel-Nr:
(PRSI61-975)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-975
Lokale Artikelnummer::
PRSI61-975
Beschreibung:
For WB starting dilution is: 1:1000. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI46-488)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
46-488
Lokale Artikelnummer::
PRSI46-488
Beschreibung:
Anti-THRB Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(PRSI7121)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7121
Lokale Artikelnummer::
PRSI7121
Beschreibung:
TSPY1L Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI60-391)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
60-391
Lokale Artikelnummer::
PRSI60-391
Beschreibung:
For WB starting dilution is: 1:1000.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI79-645)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-645
Lokale Artikelnummer::
PRSI79-645
Beschreibung:
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-637)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-637
Lokale Artikelnummer::
PRSI79-637
Beschreibung:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
VE:
1 * 100 µG
Artikel-Nr:
(PRSI61-643)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
61-643
Lokale Artikelnummer::
PRSI61-643
Beschreibung:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:50~100. For FACS starting dilution is: 1:10~50.
VE:
1 * 400 µl
New Product
Artikel-Nr:
(PRSI76-831)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-831
Lokale Artikelnummer::
PRSI76-831
Beschreibung:
The HP-3G10 monoclonal antibody specifically binds to an 80 kDa homodimer type II membrane glycoprotein from the C-type lectin superfamily, known as the human CD161 or NKR-P1A. CD161 is expressed on most natural killer cells, subsets of CD4+ and CD8+ T lymphocytes, gamma delta TCR T lymphocytes, a subset of CD3+ thymocytes, and especially on CD45RO+ T lymphocytes. Reports indicate that it may serve as a specific receptor for some natural killer cell targets and a possible stimulatory role.
VE:
1 * 0,1 mg
New Product
Artikel-Nr:
(PRSI27-597)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
27-597
Lokale Artikelnummer::
PRSI27-597
Beschreibung:
LHX3 is a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-270)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-270
Lokale Artikelnummer::
PRSI79-270
Beschreibung:
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI92-369)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-369
Lokale Artikelnummer::
PRSI92-369
Beschreibung:
Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, while it is very low in resting cells. TK1 acts as a homotetramer, and can transform thymidime to thymidine 5'-phosphate with the help of ATP.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI79-343)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-343
Lokale Artikelnummer::
PRSI79-343
Beschreibung:
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI26-636)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
26-636
Lokale Artikelnummer::
PRSI26-636
Beschreibung:
The exact function of MTHFS remains unknown.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI25-458)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-458
Lokale Artikelnummer::
PRSI25-458
Beschreibung:
ZNF197 belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.
VE:
1 * 50 µG
Preis auf Anfrage
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