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3,6-Dichloropyrazine-2-carbonitrile
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3,6-Dichloropyrazine-2-carbonitrile
Artikel-Nr:
(BOSSBS-4076R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4076R-A750
Lokale Artikelnummer::
BOSSBS-4076R-A750
Beschreibung:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3148R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3148R-A750
Lokale Artikelnummer::
BOSSBS-3148R-A750
Beschreibung:
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
VE:
1 * 100 µl
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR311442
Lokale Artikelnummer::
ORIGSR311442
Beschreibung:
CBX8 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 57332) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Artikel-Nr:
(BOSSBS-10490R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10490R-HRP
Lokale Artikelnummer::
BOSSBS-10490R-HRP
Beschreibung:
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
VE:
1 * 100 µl
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR408615
Lokale Artikelnummer::
ORIGSR408615
Beschreibung:
Cdc2a (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 12534) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Artikel-Nr:
(BOSSBS-4692R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4692R-A750
Lokale Artikelnummer::
BOSSBS-4692R-A750
Beschreibung:
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.
VE:
1 * 100 µl
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR417241
Lokale Artikelnummer::
ORIGSR417241
Beschreibung:
Mcoln3 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 171166) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR414909
Lokale Artikelnummer::
ORIGSR414909
Beschreibung:
Irak4 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 266632) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR302383
Lokale Artikelnummer::
ORIGSR302383
Beschreibung:
IL7R (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 3575) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR303654
Lokale Artikelnummer::
ORIGSR303654
Beschreibung:
PPARD (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 5467) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Artikel-Nr:
(PRSI4327)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4327
Lokale Artikelnummer::
PRSI4327
Beschreibung:
RAP80 Antibody: RAP80 was initially identified as zinc-finger containing nuclear protein that is highly expressed in testis and interacts with the retinoid-related testis-associated receptor (RTR). Later experiments revealed that RAP80 is recruited by the Coiled-coil domain 98 (CCDC98) protein to the breast cancer-1 protein BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both RAP80 and CCDC98 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either RAP80 or CCDC98 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that RAP80 and CCDC98 control only part of the DNA damage response role of BRCA1. At least four isoforms of RAP80 are known to exist.
VE:
1 * 100 µG
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR304533
Lokale Artikelnummer::
ORIGSR304533
Beschreibung:
SOX10 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 6663) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR413409
Lokale Artikelnummer::
ORIGSR413409
Beschreibung:
Prkar2a (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 19087) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR418982
Lokale Artikelnummer::
ORIGSR418982
Beschreibung:
Prkcb1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 18751) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR309292
Lokale Artikelnummer::
ORIGSR309292
Beschreibung:
NENF (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 29937) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
Lieferant:
OriGene
Hersteller-Artikelnummer::
SR416037
Lokale Artikelnummer::
ORIGSR416037
Beschreibung:
Camk2d (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 108058) Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol Included - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml 1 * 1 KIT
VE:
1 * 1 KIT
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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