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2-Fluor-4-methylphenylborons\u00E4ure
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2-Fluor-4-methylphenylborons\u00E4ure
Artikel-Nr:
(BOSSBS-1234R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1234R-A555
Lokale Artikelnummer::
BOSSBS-1234R-A555
Beschreibung:
Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF1 stimulation. Isoform A interacts with CDC2, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5462R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5462R-CY5
Lokale Artikelnummer::
BOSSBS-5462R-CY5
Beschreibung:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5462R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5462R-CY7
Lokale Artikelnummer::
BOSSBS-5462R-CY7
Beschreibung:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5460R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5460R-A647
Lokale Artikelnummer::
BOSSBS-5460R-A647
Beschreibung:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5460R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5460R-CY7
Lokale Artikelnummer::
BOSSBS-5460R-CY7
Beschreibung:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI24-258)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-258
Lokale Artikelnummer::
PRSI24-258
Beschreibung:
Anti-Flavivirus group antigen Recombinant Antibody [Clone: D1-4G2-4-15 (4G2)]
VE:
1 * 0,2 mg
Artikel-Nr:
(ACRO327850010)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
327850010
Lokale Artikelnummer::
ACRO327850010
Beschreibung:
Butylacetat 99.5+% zur elektronischen Verwendung (MOS) rückstandsfrei
VE:
1 * 1 L
Artikel-Nr:
(BOSSBS-5460R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5460R-HRP
Lokale Artikelnummer::
BOSSBS-5460R-HRP
Beschreibung:
The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Iodmonochlorid ∼0.22 N in Essigsäure (Eisessig)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(3,5-Dimethoxy-4-hydroxyphenyl)essigsäure 99%
Lieferant:
Alfa Aesar
Beschreibung:
Calciumacetat xHydrat ≥99,9965% (Metall-Basis), Puratronic®
Lieferant:
Sigma-Aldrich
Beschreibung:
Kaliumdeuteroxid 40% in D₂O, Sigma-Aldrich®
Artikel-Nr:
(BSBTPA1571)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
PA1571
Lokale Artikelnummer::
BSBTPA1571
Beschreibung:
Rabbit IgG polyclonal antibody for D(1A) dopamine receptor(DRD1) detection. Tested with WB, IHC-P in Human; Mouse; Rat.
VE:
1 * 0,1 mg
Lieferant:
Thermo Scientific
Beschreibung:
Butylacetat 99+%, reinst
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
(3,5-Bis(trifluormethyl)phenyl)essigsäure 98%
Artikel-Nr:
(BOSSBS-11234R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11234R-CY7
Lokale Artikelnummer::
BOSSBS-11234R-CY7
Beschreibung:
The Myc family, including c-Myc-, N-Myc- and L-Myc, are nuclear proteins with relatively short half lives that contribute an important role in cellular processes such as proliferation, differentiation, apoptosis and transformation. The c-Myc protein activates transcription as part of a heteromeric complex with a number of interacting partners, including Max and Mxi 1; however the transforming properties of the Myc proto-oncogene are believed to be associated with Myc-mediated transcriptional repression. A POZ domain Zn finger protein, designated Miz-1 for Myc-interacting Zn finger protein-1, is a specific target of Myc-induced gene repression. Miz-1 interacts with Myc, but not Max or other Myc partners, and binding of Myc to Miz-1 requires the helix-loop-helix domain of Myc and a short amphipathic helix located in the carboxy-terminus of Miz-1. Miz-1 associates with DNA elements on the adenovirus major late and cyclin D1 promoters and activates transcription of both promoters. Expression of Miz-1 induces potent growth arrest function, and this latency is reversed by the addition of Myc.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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