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4-Carboxy-2-nitrophenylboronsäure
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4-Carboxy-2-nitrophenylboronsäure
Artikel-Nr:
(BOSSBS-13125R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13125R-A750
Lokale Artikelnummer::
BOSSBS-13125R-A750
Beschreibung:
A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7891R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-A647
Lokale Artikelnummer::
BOSSBS-7891R-A647
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7891R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-CY5.5
Lokale Artikelnummer::
BOSSBS-7891R-CY5.5
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7891R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7891R-CY7
Lokale Artikelnummer::
BOSSBS-7891R-CY7
Beschreibung:
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
5-Carboxy-2-methoxyphenylboronsäure
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Carboxy-4-fluorphenylboronsäure
Lieferant:
COMBI-BLOCKS
Beschreibung:
2-Carboxy-3-methoxyphenylboronsäure
Artikel-Nr:
(BOSSBS-11065R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11065R-A555
Lokale Artikelnummer::
BOSSBS-11065R-A555
Beschreibung:
Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11065R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11065R-A488
Lokale Artikelnummer::
BOSSBS-11065R-A488
Beschreibung:
Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11987R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11987R-A750
Lokale Artikelnummer::
BOSSBS-11987R-A750
Beschreibung:
CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11987R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11987R-A350
Lokale Artikelnummer::
BOSSBS-11987R-A350
Beschreibung:
CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Carboxy-2-nitrophenylboronsäurepinakolester
Lieferant:
COMBI-BLOCKS
Beschreibung:
5-Carboxy-2-fluorphenylboronsäure
Artikel-Nr:
(BOSSBS-13125R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13125R-A680
Lokale Artikelnummer::
BOSSBS-13125R-A680
Beschreibung:
A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13125R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13125R-A488
Lokale Artikelnummer::
BOSSBS-13125R-A488
Beschreibung:
A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13125R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13125R-CY7
Lokale Artikelnummer::
BOSSBS-13125R-CY7
Beschreibung:
A gene on chromosome 20q13.1 encodes Eya2 (eyes absent). EYA2 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxy-terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serive-threonin)-rich amino-terminal is highly divergent. EYA2 is expressed relatively late in development in the cytoplasm of extensor tendons and ligaments of the phalangeal elements of the limb, cranial placodes, branchial arches, central nervous system, and the developing eye. Pax3 induces the expression of Eya2 in a cascade that is necessary and sufficient for myogenesis. EYA2, like EYA1, acts as a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA2 is translocated to the nucleus by Six proteins, which interact through their domain and homeodomain with EYA2. EYA2 carboxy-terminal interacts with the G Alpha z and G Alphai 2 proteins. This interaction prevents Six proteins from translocating EYA2 to the nucleus.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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