4-Chlor-1,8-naphthalsäureanhydrid
Artikel-Nr:
(BOSSBS-3769R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R-FITC
Lokale Artikelnummer::
BOSSBS-3769R-FITC
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11944R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11944R-CY5
Lokale Artikelnummer::
BOSSBS-11944R-CY5
Beschreibung:
RILPL2 is a 211 amino acid protein that belongs to the RILPL family. RILPL2 does not regulate lysosomal morphology or distribution. RILPL2 shares 32% and 18% amino acid identity with RILPL1 and RILP, respectively. RILPL2 as a novel interacting partner for the actin-based molecular motor MyoVa, and has a novel role for RILPL2 in controlling neuronal morphogenesis. It has been suggested that there is also a novel role for RILPL2 in the regulation of cellular shape and dendritic-spine morphogenesis, probably via the Rac1-Pak pathway. PCR analysis of human tissues detects highest RILPL2 expression in lung, followed by placenta. Lower expression is detected in liver, kidney, pancreas, heart and brain, but no expression is detected in skeletal muscle. The RILPL2 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 12q24.31.
VE:
1 * 100 µl
Artikel-Nr:
(HONC34658-5L)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
34658-5L
Lokale Artikelnummer::
HONC34658-5L
Beschreibung:
Chlorphenolrot-Lösung für PANPEHA-Indikatorpapier, Riedel-de Haën™
VE:
1 * 5 L
Lieferant:
Molecular Devices
Beschreibung:
The FilterMax™ series of multi-mode microplate readers can be operated as standalone instruments or can be integrated seamlessly with laboratory automation platforms. Both units are ideal for a broad range of applications, including drug discovery, genomics, proteomics and cell-based research. The patented design ensures precise performance and sensitivity across all detection modes. Units can use either automated or manual Z-Height Optimisation, and can utlise high-density well scanning for unique applications.
Lieferant:
Thermo Scientific
Beschreibung:
Appearance: White to yellow Powder
Artikel-Nr:
(USBI043374)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043374
Lokale Artikelnummer::
USBI043374
Beschreibung:
Anti-TSPAN18 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-15307R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15307R-A750
Lokale Artikelnummer::
BOSSBS-15307R-A750
Beschreibung:
C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15307R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15307R-A350
Lokale Artikelnummer::
BOSSBS-15307R-A350
Beschreibung:
C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Artikel-Nr:
(BNUM1146-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1146-50
Lokale Artikelnummer::
BTIUBNUM1146-50
Beschreibung:
Recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
VE:
1 * 50 µl
Lieferant:
Biotium
Beschreibung:
Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Artikel-Nr:
(BOSSBS-3773R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-CY7
Lokale Artikelnummer::
BOSSBS-3773R-CY7
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3769R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3769R
Lokale Artikelnummer::
BOSSBS-3769R
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-tert-Butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamate hydrate 98%
Artikel-Nr:
(SPCMCO102-50KGBL)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
CO102-50KGBL
Lokale Artikelnummer::
SPCMCO102-50KGBL
Beschreibung:
Cochineal Red A, also known as ponceau 4R, is typically synthesized from aromatic hydrocarbons and used as a synthetic food coloring. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
VE:
1 * 50 kg
Preis auf Anfrage
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