4-Carbamoyl-3-fluorobenzeneboronic+acid
Artikel-Nr:
(BOSSBS-9075R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9075R-A555
Lokale Artikelnummer::
BOSSBS-9075R-A555
Beschreibung:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2951R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2951R-CY3
Lokale Artikelnummer::
BOSSBS-2951R-CY3
Beschreibung:
Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
VE:
1 * 100 µl
Lieferant:
MP Biomedicals
Beschreibung:
Storage: Store at Room Temperature (15-30 °C), dessicate.
Ammonium persulfate is a strong oxidizing agent. It is a radical initiator. Ammonium persulfate is a polymerization catalyst used with TEMED for polyacrylamide gel formation. APS has also been utilized to study protein-protein interactions via photoinitiated crosslinking chemistry. Other applications of APS include its use as a reducer and retarder in photography, the manufacture of aniline dyes, electroplating, the decolorizing and deodorizing of oils.
Artikel-Nr:
(APOSOR89108-250MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR89108-250MG
Lokale Artikelnummer::
APOSOR89108-250MG
Beschreibung:
(S)-4-Ethyl-4-hydroxy-11-methyl-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione 250mg pack 1 * 250 mg
VE:
1 * 250 mg
New Product
Artikel-Nr:
(BOSSBS-0666R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0666R-A680
Lokale Artikelnummer::
BOSSBS-0666R-A680
Beschreibung:
Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralisation. Participates in the regulation of type I collagen deposition by osteoblasts. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8066R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8066R
Lokale Artikelnummer::
BOSSBS-8066R
Beschreibung:
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2386R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2386R-CY5.5
Lokale Artikelnummer::
BOSSBS-2386R-CY5.5
Beschreibung:
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI48-264)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
48-264
Lokale Artikelnummer::
PRSI48-264
Beschreibung:
CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-544)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-544
Lokale Artikelnummer::
PRSI28-544
Beschreibung:
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-10037R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10037R-HRP
Lokale Artikelnummer::
BOSSBS-10037R-HRP
Beschreibung:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
VE:
1 * 100 µl
Artikel-Nr:
(PRSI92-187)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-187
Lokale Artikelnummer::
PRSI92-187
Beschreibung:
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
VE:
1 * 50 µG
Lieferant:
Harvard Apparatus
Beschreibung:
The ECM 2001+ is a multifunctional electrofusion and square wave electroporation generator. The ability to generate both AC and DC waves allows for fast and efficient cell fusion in hybridoma production, hybrid cell formation, and nuclear transfer applications. This system is powerful enough to yield high transfection efficiencies for cell lines and difficult to transfect cell types including stem cells and primary cells. The gentle square wave pulse also allows for high cell viability of these cell types.
Artikel-Nr:
(APOSOR1010677-100)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-(6,7-Dihydro-1-Methyl-7-Oxo-3-Propyl-1H-Pyrazolo[4,3-d]Pyrimidin-5-yl)-N-[2-(1-Methyl-2-Pyrrolidinyl)Ethyl]-4-Propoxybenzenesulfon amide 100mg pack 1 * 100 mg
VE:
New Product
Artikel-Nr:
(PRSI91-549)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-549
Lokale Artikelnummer::
PRSI91-549
Beschreibung:
Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced; they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks down the gel matrix, allowing the spermatozoa to move more freely.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-048)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-048
Lokale Artikelnummer::
PRSI92-048
Beschreibung:
Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is absent in the thymus and peripheral blood leukocytes. MAP1LC3A is thought to take part in the formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. In addition, MAP1A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity.
VE:
1 * 50 µG
Artikel-Nr:
(APOSOR89348-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR89348-100MG
Lokale Artikelnummer::
APOSOR89348-100MG
Beschreibung:
tert-Butyl 4-(2-(benzyl(tert-butoxycarbonyl)amino)-2-oxo-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate 100mg p ack 1 * 100 mg
VE:
1 * 100 mg
New Product
Preis auf Anfrage
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