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6-Fluoro-2-methylnicotinic+acid
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6-Fluoro-2-methylnicotinic+acid
Artikel-Nr:
(BOSSBS-8525R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8525R-CY5.5
Lokale Artikelnummer::
BOSSBS-8525R-CY5.5
Beschreibung:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7015R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7015R-HRP
Lokale Artikelnummer::
BOSSBS-7015R-HRP
Beschreibung:
STK31 (Serine/threonine protein kinase 31) is similar to a mouse gene that encodes a putative protein kinase with a tudor domain, and shows testis specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7015R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7015R-A680
Lokale Artikelnummer::
BOSSBS-7015R-A680
Beschreibung:
STK31 (Serine/threonine protein kinase 31) is similar to a mouse gene that encodes a putative protein kinase with a tudor domain, and shows testis specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12313R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12313R-FITC
Lokale Artikelnummer::
BOSSBS-12313R-FITC
Beschreibung:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12313R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12313R-A488
Lokale Artikelnummer::
BOSSBS-12313R-A488
Beschreibung:
The PHEX a 749 amino acid protein that putatively consists of an intracellular, transmembrane and extracellular domain. PHEX mutations have been observed in 60-80% of hypophosphatemic rickets patients. The PHEX protein, which is a single-pass membrane protein, is also designated HYP, X-linked hypophosphatemia protein or metalloendopeptidase homolog PEX. PHEX plays an active role in bone and dentin mineralization and renal phosphate re-absorption. X-linked hypophosphatemic rickets, also designated HYP, is an X-linked dominant disorder characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9062R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9062R-A350
Lokale Artikelnummer::
BOSSBS-9062R-A350
Beschreibung:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
VE:
1 * 100 µl
Artikel-Nr:
(E703-500ML)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRCE703-500ML
Beschreibung:
Die Waschpuffer sind ideal zur Verwendung bei Anwendungen wie Western-Blot und ELISA. Sie verhindern hohen Hintergrund durch effektives Entfernen nicht gebundener Reagenzien.
VE:
1 * 500 mL
Artikel-Nr:
(BOSSBS-9095R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-CY3
Lokale Artikelnummer::
BOSSBS-9095R-CY3
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9095R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9095R-CY5
Lokale Artikelnummer::
BOSSBS-9095R-CY5
Beschreibung:
Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms. Encoded by a gene located on human chromosome 5q35.3, AGXT2L2 may have similar functions as AGXT2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13497R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13497R-CY7
Lokale Artikelnummer::
BOSSBS-13497R-CY7
Beschreibung:
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8316R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8316R-CY3
Lokale Artikelnummer::
BOSSBS-8316R-CY3
Beschreibung:
Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD21769-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD21769-100G
Lokale Artikelnummer::
BLDPBD21769-100G
Beschreibung:
Adenosin-5'-monophosphorsäure (AMP) 97%
VE:
1 * 100 g
Artikel-Nr:
(BOSSBS-2188R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2188R-CY7
Lokale Artikelnummer::
BOSSBS-2188R-CY7
Beschreibung:
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8316R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8316R-CY7
Lokale Artikelnummer::
BOSSBS-8316R-CY7
Beschreibung:
Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9062R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9062R-CY3
Lokale Artikelnummer::
BOSSBS-9062R-CY3
Beschreibung:
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8316R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8316R
Lokale Artikelnummer::
BOSSBS-8316R
Beschreibung:
Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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