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Methyl+4-cyanothiophene-2-carboxylate
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Methyl+4-cyanothiophene-2-carboxylate
Artikel-Nr:
(HECH40990103)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
40990103
Lokale Artikelnummer::
HECH40990103
Beschreibung:
Borosilicate glass coverslips for histology and microscopy.
VE:
1 * 1.000 ST
Lieferant:
Stemcell Technologies
Beschreibung:
Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford <i>et al.</i>). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford <i>et al.</i>).
Lieferant:
BIOLEGEND INC
Beschreibung:
Human recombinant IL-12 (p70) insect cells
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Irregular silica phase for preparative HPLC.
Artikel-Nr:
(614-0189)
Lieferant:
GERBER FUNKE
Hersteller-Artikelnummer::
3875
Lokale Artikelnummer::
GERB3875
Beschreibung:
Stativ, Holz, für 12 Extraktionsröhrchen nach Mojonnier
VE:
1 * 1 ST
Artikel-Nr:
(EHERC11395300)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C11395300
Lokale Artikelnummer::
EHERC11395300
Beschreibung:
4-Chlorbrenzcatechin
VE:
1 * 0,1 g
Artikel-Nr:
(BOSSBS-9584R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9584R-A647
Lokale Artikelnummer::
BOSSBS-9584R-A647
Beschreibung:
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-å and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9584R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9584R-A750
Lokale Artikelnummer::
BOSSBS-9584R-A750
Beschreibung:
Membrane receptor Signalling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3 appears to be activated by both while Stat3 is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated Signalling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15307R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15307R-A680
Lokale Artikelnummer::
BOSSBS-15307R-A680
Beschreibung:
C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15307R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15307R-A488
Lokale Artikelnummer::
BOSSBS-15307R-A488
Beschreibung:
C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
VE:
1 * 100 µl
Artikel-Nr:
(ACRO147865000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
147865000
Lokale Artikelnummer::
ACRO147865000
Beschreibung:
EDTA Trinatriumsalz Hydrat 98%
VE:
1 * 500 g
Lieferant:
BROTHER
Beschreibung:
Label printer tape, Abmessungen: 12 mm×15 m, Polyester, Schwarz/weiß
Lieferant:
Thermo Scientific
Beschreibung:
3,4-Dimethyl-o-phenylendiamin
Artikel-Nr:
(PIER66432)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
66432
Lokale Artikelnummer::
PIER66432
Beschreibung:
Slide-A-lyzer cassette float buoys (for 12 ml cassettes) , Pierce™
VE:
1 * 8 ST
Artikel-Nr:
(BOSSBS-13105R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13105R-A680
Lokale Artikelnummer::
BOSSBS-13105R-A680
Beschreibung:
Endoplasmic reticulum proteins (ERps) are widely expressed proteins and localize to the ER. ERp19, ERp29, ERp46, ERp57 and ERp72 may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases, phospholipases or a combination of these. ERp19, also designated thioredoxin domain-containing protein 12 (TXNDC12), and ERp46, also designated thioredoxin domain containing 5 (TXNDC5), belong to the thioredoxin superfamily and contain a thioredoxin fold with a consensus active-site sequence (CxxC). Both ERp19 and ERp46 are widely expressed ER luminal proteins that are most abundant in the liver and are enriched in purified liver ER vesicles. ERp19 shows significant protein thiol-disulfide oxidase activity in vitro, which is dependent on the presence of both active-site cysteines.
VE:
1 * 100 µl
Artikel-Nr:
(SIMPT110-5)
Lieferant:
Simport Scientific
Hersteller-Artikelnummer::
T110-5
Lokale Artikelnummer::
SIMPT110-5
Beschreibung:
PP. The 1,2 ml capacity round bottom deep well plate (1 ml when capped) is easy to empty completely and ideal for culturing bacterial cells. It can withstand centrifugation up to 6000 ×g and is DMSO resistant.
VE:
1 * 24 ST
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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