(1S,3R)-3-Aminocyclopentanecarboxylic+acid
Artikel-Nr:
(BOSSBS-0334R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0334R
Lokale Artikelnummer::
BOSSBS-0334R
Beschreibung:
Anti-MYCT1 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0979R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0979R-HRP
Lokale Artikelnummer::
BOSSBS-0979R-HRP
Beschreibung:
Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3890R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3890R-A350
Lokale Artikelnummer::
BOSSBS-3890R-A350
Beschreibung:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4045R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4045R-CY5
Lokale Artikelnummer::
BOSSBS-4045R-CY5
Beschreibung:
KHK encodes the gene ketohexokinase that catalyzes conversion of fructose to fructose 1 phosphate. The splice variant presented encodes the highly active form found in liver, renal cortex, and small intestine, while the alternate variant encodes the lower activity form found in most other tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1820R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1820R-A647
Lokale Artikelnummer::
BOSSBS-1820R-A647
Beschreibung:
High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12481R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12481R-A555
Lokale Artikelnummer::
BOSSBS-12481R-A555
Beschreibung:
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1517R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1517R-CY3
Lokale Artikelnummer::
BOSSBS-1517R-CY3
Beschreibung:
Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5238R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5238R-A555
Lokale Artikelnummer::
BOSSBS-5238R-A555
Beschreibung:
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1459R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1459R-CY3
Lokale Artikelnummer::
BOSSBS-1459R-CY3
Beschreibung:
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15462R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15462R-CY7
Lokale Artikelnummer::
BOSSBS-15462R-CY7
Beschreibung:
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyse the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6804R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6804R
Lokale Artikelnummer::
BOSSBS-6804R
Beschreibung:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7077R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7077R-A488
Lokale Artikelnummer::
BOSSBS-7077R-A488
Beschreibung:
Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1336R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1336R-CY5
Lokale Artikelnummer::
BOSSBS-1336R-CY5
Beschreibung:
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F() activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6562R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6562R-CY5.5
Lokale Artikelnummer::
BOSSBS-6562R-CY5.5
Beschreibung:
Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2693R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2693R-A750
Lokale Artikelnummer::
BOSSBS-2693R-A750
Beschreibung:
Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9428R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9428R-HRP
Lokale Artikelnummer::
BOSSBS-9428R-HRP
Beschreibung:
Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
VE:
1 * 100 µl
Preis auf Anfrage
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