4-Fluorobenzo[d]thiazol-2(3H)-one
Artikel-Nr:
(BOSSBS-11652R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11652R-CY7
Lokale Artikelnummer::
BOSSBS-11652R-CY7
Beschreibung:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1711R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1711R-FITC
Lokale Artikelnummer::
BOSSBS-1711R-FITC
Beschreibung:
PCDHA6 (Protocadherin alpha 6) is a member of the protocadherin family, a subgroup of the cadherin superfamily. Protocadherins are neural cadherin-like cell adhesion proteins that are integral membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific neuronal connections in the brain. PCDHA6 is one of fifteen tandemly arranged genes within the alpha cluster of protocadherin genes on 5q31.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8525R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8525R-FITC
Lokale Artikelnummer::
BOSSBS-8525R-FITC
Beschreibung:
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11408R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-HRP
Lokale Artikelnummer::
BOSSBS-11408R-HRP
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5714R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5714R-A750
Lokale Artikelnummer::
BOSSBS-5714R-A750
Beschreibung:
OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8021R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8021R-CY7
Lokale Artikelnummer::
BOSSBS-8021R-CY7
Beschreibung:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6283R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6283R-CY3
Lokale Artikelnummer::
BOSSBS-6283R-CY3
Beschreibung:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6419R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6419R-CY5.5
Lokale Artikelnummer::
BOSSBS-6419R-CY5.5
Beschreibung:
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5015R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5015R-A750
Lokale Artikelnummer::
BOSSBS-5015R-A750
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyse the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM1057-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM1057-50
Lokale Artikelnummer::
BTIUBNUM1057-50
Beschreibung:
Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-2709R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2709R-A647
Lokale Artikelnummer::
BOSSBS-2709R-A647
Beschreibung:
High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2709R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2709R-A680
Lokale Artikelnummer::
BOSSBS-2709R-A680
Beschreibung:
High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12388R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12388R-CY7
Lokale Artikelnummer::
BOSSBS-12388R-CY7
Beschreibung:
KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7779R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7779R-CY5.5
Lokale Artikelnummer::
BOSSBS-7779R-CY5.5
Beschreibung:
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15559R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15559R
Lokale Artikelnummer::
BOSSBS-15559R
Beschreibung:
IFT140 is a gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5015R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5015R-CY3
Lokale Artikelnummer::
BOSSBS-5015R-CY3
Beschreibung:
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].
VE:
1 * 100 µl
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