4-Fluorobenzo[d]thiazol-2(3H)-one
Artikel-Nr:
(BOSSBS-15409R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15409R-FITC
Lokale Artikelnummer::
BOSSBS-15409R-FITC
Beschreibung:
CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalysing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6947R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6947R-CY7
Lokale Artikelnummer::
BOSSBS-6947R-CY7
Beschreibung:
KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15409R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15409R-CY3
Lokale Artikelnummer::
BOSSBS-15409R-CY3
Beschreibung:
CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalysing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7335R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7335R-CY3
Lokale Artikelnummer::
BOSSBS-7335R-CY3
Beschreibung:
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7335R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7335R-CY5.5
Lokale Artikelnummer::
BOSSBS-7335R-CY5.5
Beschreibung:
MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10266R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10266R
Lokale Artikelnummer::
BOSSBS-10266R
Beschreibung:
Tbx3 gene is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. Tbx3 is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0753R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0753R
Lokale Artikelnummer::
BOSSBS-0753R
Beschreibung:
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5914R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5914R
Lokale Artikelnummer::
BOSSBS-5914R
Beschreibung:
Carbonic anhydrase is a family of metalloenzymes (enzymes that contain one or more metal atoms as a functional component of the enzyme) that catalyze the rapid interconversion of carbon dioxide and water into carbonic acid and protons. It also converts bicarbonate in carbon dioxide and water. This reaction occurs spontaneously in aqueous solution, but does so slowly. Carbonic anhydrase can greatly increase the rate of the reaction, with typical catalytic rates of the different forms of this enzyme ranging between 104 and 106 reactions per second. The active site of most carbonic anhydrases contains a zinc ion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13325R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13325R-CY3
Lokale Artikelnummer::
BOSSBS-13325R-CY3
Beschreibung:
GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12906R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12906R-CY5
Lokale Artikelnummer::
BOSSBS-12906R-CY5
Beschreibung:
KLHL28 is a 571 amino acid protein similar to the Drosophila kelch protein. KLHL26 contains six kelch repeats and one BTB (POZ) domain. The BTB (broad complex, tramtrack and bric-a-brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL28 is expressed as two isoforms produced by alternative splicing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5825R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5825R-CY3
Lokale Artikelnummer::
BOSSBS-5825R-CY3
Beschreibung:
The PCDHA12 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five, which demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins which may play a role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0394R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0394R
Lokale Artikelnummer::
BOSSBS-0394R
Beschreibung:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13034R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13034R-CY7
Lokale Artikelnummer::
BOSSBS-13034R-CY7
Beschreibung:
DTYMK is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13325R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13325R-CY5
Lokale Artikelnummer::
BOSSBS-13325R-CY5
Beschreibung:
GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0945R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0945R-CY3
Lokale Artikelnummer::
BOSSBS-0945R-CY3
Beschreibung:
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0641R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0641R-HRP
Lokale Artikelnummer::
BOSSBS-0641R-HRP
Beschreibung:
Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
![]()
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||