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3-Amino-6-(4-fluorophenyl)pyridazine
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3-Amino-6-(4-fluorophenyl)pyridazine
Artikel-Nr:
(BOSSBS-12379R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12379R-HRP
Lokale Artikelnummer::
BOSSBS-12379R-HRP
Beschreibung:
Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5308R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5308R-HRP
Lokale Artikelnummer::
BOSSBS-5308R-HRP
Beschreibung:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3112R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3112R-HRP
Lokale Artikelnummer::
BOSSBS-3112R-HRP
Beschreibung:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Artikel-Nr:
(USBI041365)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041365
Lokale Artikelnummer::
USBI041365
Beschreibung:
Anti-S1PR5 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-4062R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4062R-CY3
Lokale Artikelnummer::
BOSSBS-4062R-CY3
Beschreibung:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4062R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4062R-CY5.5
Lokale Artikelnummer::
BOSSBS-4062R-CY5.5
Beschreibung:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4062R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4062R
Lokale Artikelnummer::
BOSSBS-4062R
Beschreibung:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors; UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(USBI123069)
Lieferant:
US Biological
Hersteller-Artikelnummer::
123069
Lokale Artikelnummer::
USBI123069
Beschreibung:
Anti-AGPAT5 Mouse Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-3497R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3497R-CY3
Lokale Artikelnummer::
BOSSBS-3497R-CY3
Beschreibung:
NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7541R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7541R-A555
Lokale Artikelnummer::
BOSSBS-7541R-A555
Beschreibung:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4045R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4045R-A350
Lokale Artikelnummer::
BOSSBS-4045R-A350
Beschreibung:
KHK encodes the gene ketohexokinase that catalyzes conversion of fructose to fructose 1 phosphate. The splice variant presented encodes the highly active form found in liver, renal cortex, and small intestine, while the alternate variant encodes the lower activity form found in most other tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6177R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6177R-A680
Lokale Artikelnummer::
BOSSBS-6177R-A680
Beschreibung:
RAB proteins are GTPases that regulate vesicular trafficking and reside in specific intracellular compartments. RAB9 has been localised to components of the endocytic/exocytic pathway. It has been implicated in the recycling of membrane receptors, such as the mannose 6-phosphate receptor from early endosomes to the trans Golgi network.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6177R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6177R-A350
Lokale Artikelnummer::
BOSSBS-6177R-A350
Beschreibung:
RAB proteins are GTPases that regulate vesicular trafficking and reside in specific intracellular compartments. RAB9 has been localized to components of the endocytic/exocytic pathway. It has been implicated in the recycling of membrane receptors, such as the mannose 6-phosphate receptor from early endosomes to the trans Golgi network.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3294R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3294R-A647
Lokale Artikelnummer::
BOSSBS-3294R-A647
Beschreibung:
Protein which catalyzes the phosphorylation of serine or threonine residues on target proteins by using ATP as phosphate donor. Such phosphorylation may cause changes in the function of the target protein. Protein kinases share a conserved catalytic core common to both serine/ threonine and tyrosine protein kinases.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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