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Methyl+3-bromo-2-chloro-6-fluorobenzoate
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Methyl+3-bromo-2-chloro-6-fluorobenzoate
Artikel-Nr:
(BOSSBS-9924R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9924R-A680
Lokale Artikelnummer::
BOSSBS-9924R-A680
Beschreibung:
WDFY3 was identified in a screen for phosphatidylinositol 3 phosphate binding proteins. The FYVE domain is a zinc binding domain found in many PtdIns binding proteins and is proposed to target proteins to membrane lipids. WDFY3 has been shown localised to the nuclear membrane and within autophagic membranes and it is proposed to function as a link between protein aggregates and the autophagic machinery. WDFY3 is also known as autophagy linked FYVE protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9027R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9027R-CY3
Lokale Artikelnummer::
BOSSBS-9027R-CY3
Beschreibung:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6417R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6417R-CY7
Lokale Artikelnummer::
BOSSBS-6417R-CY7
Beschreibung:
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion and aggregation. Plays a role in platelet activation signaling triggered by GPCRs, alpha-IIb/beta-3 integrins (ITGA2B/ ITGB3) and ITAM (immunoreceptor tyrosine-based activation motif)-bearing receptors such as GP6. Regulates the strength of adhesion of ITGA2B/ ITGB3 activated receptors necessary for the cellular transmission of contractile forces. Required for platelet aggregation induced by F2 (thrombin) and thromboxane A2 (TXA2). Has a role in cell survival. May have a role in cell migration. Involved in the early stage of autophagosome formation. Modulates the intracellular level of PtdIns3P (Phosphatidylinositol 3-phosphate) and activates PIK3C3 kinase activity. May act as a scaffold, independently of its lipid kinase activity to positively regulate autophagy. May have a role in insulin signaling as scaffolding protein in which the lipid kinase activity is not required. May have a kinase-independent function in regulating cell proliferation and in clathrin-mediated endocytosis. Mediator of oncogenic signal in cell lines lacking PTEN. The lipid kinase activity is necessary for its role in oncogenic transformation. Required for the growth of ERBB2 and RAS driven tumors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7112R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7112R-A680
Lokale Artikelnummer::
BOSSBS-7112R-A680
Beschreibung:
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganisation of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralisation and bone homeostasis (By similarity). Plays a role in responses to oxidised 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
VE:
1 * 100 µl
Artikel-Nr:
(510-0179)
Lieferant:
WHITEHOUSE
Hersteller-Artikelnummer::
SS404
Lokale Artikelnummer::
WHITSS404
Beschreibung:
Einzigartige Methode der Siebkalibrierung mit Mikrokugeln. Anwendbar für alle Siebe von 20 bis 3350 µm.
VE:
1 * 5 ST
Artikel-Nr:
(BOSSBS-6670R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6670R-HRP
Lokale Artikelnummer::
BOSSBS-6670R-HRP
Beschreibung:
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9027R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9027R-FITC
Lokale Artikelnummer::
BOSSBS-9027R-FITC
Beschreibung:
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011].
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
4-Methylumbelliferyl phosphate, Sigma-Aldrich®
Lieferant:
Alfa Aesar
Beschreibung:
Tris(hydroxymethyl)aminomethan (TRIS, Trometamol) 99,0-101,0% (Trockenmasse)
Artikel-Nr:
(BOSSBS-11457R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11457R-A680
Lokale Artikelnummer::
BOSSBS-11457R-A680
Beschreibung:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
VE:
1 * 100 µl
Artikel-Nr:
(SIALP3657-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
P3657-1G
Lokale Artikelnummer::
SIALP3657-1G
Beschreibung:
Pyridoxal-5'-phosphat, Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Tris(hydroxymethyl)aminomethan (TRIS, Trometamol), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Tris(hydroxymethyl)aminomethan (TRIS, Trometamol), Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Trichloracetylisocyanat, Sigma-Aldrich®
Artikel-Nr:
(USBI133418)
Lieferant:
US Biological
Hersteller-Artikelnummer::
133418
Lokale Artikelnummer::
USBI133418
Beschreibung:
Anti-SLC20A1 Mouse Monoclonal Antibody [clone: 6A9-F2]
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-11457R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11457R-A750
Lokale Artikelnummer::
BOSSBS-11457R-A750
Beschreibung:
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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