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5-Amino-7-azaindole
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5-Amino-7-azaindole
Lieferant:
Sigma-Aldrich
Beschreibung:
3,4-Dimethoxybenzylalkohol, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-5915R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-CY3
Lokale Artikelnummer::
BOSSBS-5915R-CY3
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5915R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-CY5
Lokale Artikelnummer::
BOSSBS-5915R-CY5
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(YSIL1579)
Lieferant:
YSI LIFE SCIENCE
Hersteller-Artikelnummer::
1579
Lokale Artikelnummer::
YSIL1579
Beschreibung:
Carbonate buffer concentrate for use with methanol membranes and ethanol membranes. Reconstitute to make 1 litre.
VE:
1 * 1 L
Artikel-Nr:
(SIAL533033-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
533033-5G
Lokale Artikelnummer::
SIAL533033-5G
Beschreibung:
4-Brom-2,6-difluorbenzylalkohol, Sigma-Aldrich®
VE:
1 * 5 g
Artikel-Nr:
(REST30439)
Lieferant:
Restek
Hersteller-Artikelnummer::
30439
Lokale Artikelnummer::
REST30439
Beschreibung:
Calibration mix contains bromomethane (methyl bromide), chloroethane (ethyl chloride), chloromethane (methyl chloride), dichlorodifluoromethane (CFC-12), trichlorofluoromethane (CFC-11), vinyl chloride.
VE:
1 * 1 ST
Artikel-Nr:
(REST30207)
Lieferant:
Restek
Hersteller-Artikelnummer::
30207
Lokale Artikelnummer::
REST30207
Beschreibung:
100-octane, low-lead fuel used in piston-type aircraft.
VE:
1 * 1 mL
Artikel-Nr:
(CHMPFL13215.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13215.POR
Lokale Artikelnummer::
CHMPFL13215.POR
Beschreibung:
2-Brom-4-fluorbenzylalkohol
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-5915R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5915R-HRP
Lokale Artikelnummer::
BOSSBS-5915R-HRP
Beschreibung:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE:
1 * 100 µl
Artikel-Nr:
(MAYBCC04009.10)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
CC04009.10
Lokale Artikelnummer::
MAYBCC04009.10
Beschreibung:
2-Pyridinylmethanol
VE:
1 * 10 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(FLUO018219-10G)
Lieferant:
FLUOROCHEM
Hersteller-Artikelnummer::
018219-10G
Lokale Artikelnummer::
FLUO018219-10G
Beschreibung:
4-Benzyloxybenzylalkohol
VE:
1 * 10 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(CHMPFL13762.POR)
Lieferant:
CHEMPUR
Hersteller-Artikelnummer::
FL13762.POR
Lokale Artikelnummer::
CHMPFL13762.POR
Beschreibung:
2,5-Bis(trifluormethyl)benzylalkohol
VE:
1 * 1 ST
Lieferant:
FLUOROCHEM
Beschreibung:
2,6-Difluorbenzylalkohol
Artikel-Nr:
(SIAL190284-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
190284-25G
Lokale Artikelnummer::
SIAL190284-25G
Beschreibung:
3-Phenoxybenzylalkohol, Sigma-Aldrich®
VE:
1 * 25 g
Artikel-Nr:
(SIAL188263-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
188263-5G
Lokale Artikelnummer::
SIAL188263-5G
Beschreibung:
3-Methyl-2-nitrobenzylalkohol, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
FLUOROCHEM
Beschreibung:
2,6-Difluoro-3-methylbenzyl alcohol
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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