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5,5'-Dibrom-2,2'-bithiophen
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5,5'-Dibrom-2,2'-bithiophen
Artikel-Nr:
(BOSSBS-11160R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11160R-CY7
Lokale Artikelnummer::
BOSSBS-11160R-CY7
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGC4 (protocadherin gamma subfamily C, 4) is a 938 amino acid single-pass type I membrane protein that localizes to the cell membrane and contains six cadherin domains. Expressed as two alternatively spliced isoforms, PCDHGC4 functions as a potential calcium-dependent cell adhesion protein that is thought to be involved in the establishment and maintenance of neuronal connections within the brain. The gene encoding PCDHGC4 maps to a protocadherin gamma gene cluster which is localized to chromosome 5 and contains over 22 protocadherin genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11160R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11160R-CY5
Lokale Artikelnummer::
BOSSBS-11160R-CY5
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGC4 (protocadherin gamma subfamily C, 4) is a 938 amino acid single-pass type I membrane protein that localizes to the cell membrane and contains six cadherin domains. Expressed as two alternatively spliced isoforms, PCDHGC4 functions as a potential calcium-dependent cell adhesion protein that is thought to be involved in the establishment and maintenance of neuronal connections within the brain. The gene encoding PCDHGC4 maps to a protocadherin gamma gene cluster which is localized to chromosome 5 and contains over 22 protocadherin genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12904R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12904R-CY3
Lokale Artikelnummer::
BOSSBS-12904R-CY3
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11060R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11060R-CY5
Lokale Artikelnummer::
BOSSBS-11060R-CY5
Beschreibung:
Otoancorin, also known as OTOA, CT108 or DFNB22, is a 1,153 amino acid protein belonging to the stereocilin family. Expressed in the inner ear and restricted to the interface between the apical surface of sensory epithelia, otoancorin is suggested to act as an adhesion molecule. Otoancorin ensures the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in the gene encoding otoancorin leads to deafness autosomal recessive type 22 (DFNB22), which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain or the area of the brain that receives sound information. Existing as three alternatively spliced isoforms, otoancorin is encoded by a gene located on human chromosome 16p12.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11160R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11160R-CY3
Lokale Artikelnummer::
BOSSBS-11160R-CY3
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGC4 (protocadherin gamma subfamily C, 4) is a 938 amino acid single-pass type I membrane protein that localizes to the cell membrane and contains six cadherin domains. Expressed as two alternatively spliced isoforms, PCDHGC4 functions as a potential calcium-dependent cell adhesion protein that is thought to be involved in the establishment and maintenance of neuronal connections within the brain. The gene encoding PCDHGC4 maps to a protocadherin gamma gene cluster which is localized to chromosome 5 and contains over 22 protocadherin genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12904R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12904R-CY7
Lokale Artikelnummer::
BOSSBS-12904R-CY7
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3999R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3999R
Lokale Artikelnummer::
BOSSBS-3999R
Beschreibung:
Summary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5183R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5183R-CY5
Lokale Artikelnummer::
BOSSBS-5183R-CY5
Beschreibung:
The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(EHERC20008500)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C20008500
Lokale Artikelnummer::
EHERC20008500
Beschreibung:
2,2',3,4,4'-Pentachlorbiphenyl (PCB Nr. 85)
VE:
1 * 10 mg
Artikel-Nr:
(EHERC20004400)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C20004400
Lokale Artikelnummer::
EHERC20004400
Beschreibung:
2,2',3,5'-Tetrachlorbiphenyl (PCB Nr. 44)
VE:
1 * 25 mg
Artikel-Nr:
(BOSSBS-9656R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9656R
Lokale Artikelnummer::
BOSSBS-9656R
Beschreibung:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The FAM78A gene product has been provisionally designated FAM78A pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI76-376)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
76-376
Lokale Artikelnummer::
PRSI76-376
Beschreibung:
The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck).Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
VE:
1 * 0,025 mg
New Product
Artikel-Nr:
(PROOCIL-PCB-138-C)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-138-C
Lokale Artikelnummer::
PROOCIL-PCB-138-C
Beschreibung:
2,2',3,4,4',5'-Hexachlorbiphenyl (PCB Nr. 138)
VE:
1 * 5 mg
Artikel-Nr:
(PRSIPM-5201)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
PM-5201
Lokale Artikelnummer::
PRSIPM-5201
Beschreibung:
CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
VE:
1 * 100 µG
Artikel-Nr:
(PROOCIL-PCB-51-C)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-51-C
Lokale Artikelnummer::
PROOCIL-PCB-51-C
Beschreibung:
2,2',4,6'-Tetrachlorbiphenyl (PCB Nr. 51)
VE:
1 * 5 mg
Artikel-Nr:
(PROOCIL-PCB-48-C)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CIL-PCB-48-C
Lokale Artikelnummer::
PROOCIL-PCB-48-C
Beschreibung:
2,2',4,5-Tetrachlorbiphenyl (PCB Nr. 48)
VE:
1 * 5 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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