5-Isochinolinborons\\u00E4ure+Hydrochlorid
Lieferant:
Cayman Chemical
Beschreibung:
(±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)11(12)-EET has been shown, along with (±)8(9)-EET, to play a role in the recovery of depleted Ca²⁺ pools in cultured smooth muscle cells.
Artikel-Nr:
(BOSSBS-13545R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R
Lokale Artikelnummer::
BOSSBS-13545R
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-CY7
Lokale Artikelnummer::
BOSSBS-13545R-CY7
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13545R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13545R-CY3
Lokale Artikelnummer::
BOSSBS-13545R-CY3
Beschreibung:
Guanylate cyclases belong to the adenylyl cyclase class-4/guanylyl cyclase family. There are two forms of guanylate cyclase. The soluble form, known as GCS or sGC, act as receptors for nitric oxide (NO). The membrane-bound receptor form, known as GC, are peptide hormone receptors. GCS is a cGMP-synthesizing enzyme, which is the major receptor for the neurotransmitter nitric oxide. It plays a crucial role in smooth muscle contractility, platelet reactivity and neurotransmission. GCS is a heme-containing heterodimer, consisting of one alpha subunit and one beta subunit. The heme moeity mediates NO activation, and this heme group also binds carbon monoxide (CO), which weakly stimulates the enzyme. Both NO and CO stimulation are enhanced by the allosteric activator 3-(5'-hydroxymethyl-2'furyl)-benzyl-indazole, YC-1. YC-1 can also stimulate GCS in a NO-independent manner. Both alpha and beta subunits are required for cGMP generation, and at least two isoforms exist for each subunit. Heterodimers consisting of alpha-1/beta-1 and alpha-2/beta-1 have been identified, and both display similar enzymatic activity. The distribution of the beta-2 subunit seems to be much more restricted than the beta-1 subunit, with predominant expression in kidney and liver.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD322210-250MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD322210-250MG
Lokale Artikelnummer::
BLDPBD322210-250MG
Beschreibung:
2'-Fluoro-4-pentyl-4''-propyl-1,1':4',1''-terphenyl 95%
VE:
1 * 250 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4,4'-Bis(dimethylamino)benzophenon
Artikel-Nr:
(42446-100MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
42446-100MG
Lokale Artikelnummer::
SUPL42446-100MG
Beschreibung:
Organic Standard, Bis(8-methylnonyl) phthalate
VE:
1 * 100 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,4-Bis(trifluormethyl)-2-nitrobenzol 97%
Artikel-Nr:
(BLDPBD01430000-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01430000-1G
Lokale Artikelnummer::
BLDPBD01430000-1G
Beschreibung:
4',4''',4'''''-Nitrilotris(([1,1'-biphenyl]-3-carboxylic acid)) 95%
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD01445166-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD01445166-1G
Lokale Artikelnummer::
BLDPBD01445166-1G
Beschreibung:
4'',4''''',4''''''''-Nitrilotris(([1,1':4',1''-terphenyl]-4-carboxylic acid)) 95%
VE:
1 * 1 g
Lieferant:
Sigma-Aldrich
Beschreibung:
2',3'-Dideoxyinosin, Sigma-Aldrich®
Artikel-Nr:
(30585-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
30585-1G
Lokale Artikelnummer::
SUPL30585-1G
Beschreibung:
Bis(1-butylpentyl)decane-1,10-diyl diglutarate, was used for the preparation of optode membranes, which are sodium selective and are based on neutral ionophore, primarily used for the characterization of total sodium concentration in human blood plasma.
VE:
1 * 1 g
Artikel-Nr:
(APOSOR360578-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR360578-1G
Lokale Artikelnummer::
APOSOR360578-1G
Beschreibung:
(S)-2,2'-Dimethoxy-1,1'-binaphthalin-3,3'-diboronsäure 98%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,1-Cyclopropane dimethanol cyclic sulphite 98%
Lieferant:
Sigma-Aldrich
Beschreibung:
Pyridoxal Hydrochlorid, Sigma-Aldrich®
Preis auf Anfrage
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