5-Amino-2-fluor-3-methylpyridin
Artikel-Nr:
(BOSSBS-13357R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13357R-A488
Lokale Artikelnummer::
BOSSBS-13357R-A488
Beschreibung:
ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8163R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8163R-A750
Lokale Artikelnummer::
BOSSBS-8163R-A750
Beschreibung:
WDR79 contains six WD (tryptophan-aspartate) repeat domains found in a number of proteins that function as adaptor molecules in signal transduction and cytoskeletal organization. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. The function of the WDR79 protein has not been characterized, however significant and consistent single nucleotide polymorphisms in the WDR79 gene have been found to be associated with ER negative breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12177R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12177R-A680
Lokale Artikelnummer::
BOSSBS-12177R-A680
Beschreibung:
Voltage-gated K+ channels in the plasma membrane are important regulators of electrical Signalling, controlling the repolarisation and the frequency of action potentials in neurons, muscles and other excitable cells. KCNT2 is a 1,135 amino acid multi-pass transmembrane protein belonging to the potassium channel family (calcium-activated subfamily) of proteins. KCNT2 produces rapidly activating outward rectifier potassium currents in reponse to high intracellular sodium and chloride levels. Its channel activity is inhibited by ATP, inhalation anesthetics, such as isoflourane, and upon stimulation of G-protein coupled receptors, such as mAChR M1 and GluR-1. There are four isoforms of KCNT2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11468R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11468R-A750
Lokale Artikelnummer::
BOSSBS-11468R-A750
Beschreibung:
Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo A, B and C. NgBR (Nogo-B receptor), also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B. Through this interaction, NgBR is involved in the regulation of vascular remodeling and angiogenesis. NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilisation. Knockdown of NgBR mRNA leads to decreased NPC2 levels, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD3328-100G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD3328-100G
Lokale Artikelnummer::
BLDPBD3328-100G
Beschreibung:
5-Brom-2-chlor-3-methylpyridin 98%
VE:
1 * 100 g
Lieferant:
Alfa Aesar
Beschreibung:
2-Methyl-3-pyridinol ≥99%
Artikel-Nr:
(BOSSBS-13042R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13042R-A750
Lokale Artikelnummer::
BOSSBS-13042R-A750
Beschreibung:
DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11713R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11713R-A680
Lokale Artikelnummer::
BOSSBS-11713R-A680
Beschreibung:
Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12476R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12476R-A680
Lokale Artikelnummer::
BOSSBS-12476R-A680
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ANKZF1 (ankyrin repeat and zinc finger domain containing 1), also known as ZNF744, is 726 amino acids in length and lacks a KRAB domain but contains one C2H2-type zinc finger and two ANK repeats. The gene encoding ANKZF1 localizes to chromosome 2.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR33026-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR33026-1G
Lokale Artikelnummer::
APOSOR33026-1G
Beschreibung:
1-[6-(4-Methoxyphenoxy)-2-methylpyridin-3-yl]ethan-1-one, tech
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
tert-Butyl 2-chloro-5-methylpyridin-4-ylcarbamate
Artikel-Nr:
(APOSOR53214-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR53214-1G
Lokale Artikelnummer::
APOSOR53214-1G
Beschreibung:
2-Methylpyridine-5-boronic acid hydrochloride 98%
VE:
1 * 1 g
Lieferant:
Alfa Aesar
Beschreibung:
5-Brom-2-chlor-3-methylpyridin 98%
Artikel-Nr:
(BLDPBD19008-10G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD19008-10G
Lokale Artikelnummer::
BLDPBD19008-10G
Beschreibung:
3-Brom-2-chlor-6-methylpyridin 98%
VE:
1 * 10 g
Artikel-Nr:
(APOSOR345364-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR345364-5G
Lokale Artikelnummer::
APOSOR345364-5G
Beschreibung:
2-Bromo-5-hydroxy-3-methylpyridine 98%
VE:
1 * 5 g
Preis auf Anfrage
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