5-Amino-2-nitrobenzoes\\\\u00E4ure
Artikel-Nr:
(BOSSBS-12497R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12497R-FITC
Lokale Artikelnummer::
BOSSBS-12497R-FITC
Beschreibung:
Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins (2). The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages (3,4). The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues (5–7). The human apoC-III gene maps to chromosome 11q23 and encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase (8). The human apoC-IV gene maps to chromosome 19q13.2 and encodes a 127 amino acid protein that is primarily expressed in the liver (9,10).
VE:
1 * 100 µl
Artikel-Nr:
(MOLE72628801-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
72628801-25G
Lokale Artikelnummer::
MOLE72628801-25G
Beschreibung:
2-Amino-6-methoxybenzothiazol
VE:
1 * 25 g
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Lieferant:
Thermo Scientific
Beschreibung:
4-Amino-o-anissäure
Lieferant:
Sigma-Aldrich
Beschreibung:
(S)-(-)-4-Amino-2-hydroxybuttersäure, Sigma-Aldrich®
Lieferant:
VWR Chemicals
Beschreibung:
EDTA Dinatriumsalz Dihydrat 99,0-101,0%, AnalaR NORMAPUR® ACS, Reag. Ph. Eur. analytisches Reagens
Lieferant:
Alfa Aesar
Beschreibung:
Excellent colorimetric substrate for detection of horseradish peroxidase labelled probes; particularly useful in ELISA techniques, blue result can be read spectrophotometrically at 370 or 650 nm3,3',5,5'-Tetramethylbenzidine is used as a clinical reagent for testing blood.
Lieferant:
FLUOROCHEM
Beschreibung:
2-Amino-4-methylpyridin
Artikel-Nr:
(MOLEM58220382)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M58220382
Lokale Artikelnummer::
MOLEM58220382
Beschreibung:
(S)-(+)-2-Amino-1-propanol
VE:
1 * 5 g
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Artikel-Nr:
(BOSSBS-8471R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8471R-A647
Lokale Artikelnummer::
BOSSBS-8471R-A647
Beschreibung:
Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin and F-box proteins act as protein-ubiquitin ligases and mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6792R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6792R-CY3
Lokale Artikelnummer::
BOSSBS-6792R-CY3
Beschreibung:
The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7961R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7961R-CY3
Lokale Artikelnummer::
BOSSBS-7961R-CY3
Beschreibung:
Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 22–24 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases; most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13189R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13189R-CY7
Lokale Artikelnummer::
BOSSBS-13189R-CY7
Beschreibung:
Amines, including those present on proteins, spontaneously react with glucose to make fructosamines in a reaction termed glycation. Fructosamine 3-kinase (FN3K), a 309-amino acid enzyme initially identified in erythrocytes, catalyzes the ATP-dependent phosphorylation of the third carbon on both D- and L-fructosamines, leading to their destabilization and eventually, their removal from the protein. FN3K is a monomer that is ubiquitously expressed in mammalian tissue and phosphorylates both low molecular mass and protein-bound fructosamines which are formed as a result of glycation of glucose with primary amines. FN3K protects proteins from the harmful effects of nonenzymatic glycation, and may also be involved in peptide repair and cell metabolism. FN3KRP (fructosamine-3-kinase-related protein) is a 309 amino acid protein that is expressed in erythrocytes, bone marrow, spleen, brain and kidney and belongs to the fructosamine kinase family. FN3KRP functions to phosphorylate psicoamines and ribulosamines on the third carbon of their sugar moiety, thereby leading to the deglycation of the target amines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8358R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8358R-CY5.5
Lokale Artikelnummer::
BOSSBS-8358R-CY5.5
Beschreibung:
Kelch domain-containing protein 8A (KLHDC8A) is a 350 amino acid protein. KLHDC8A contains seven kelch repeats, each of which is an approximately 50 amino acid long conserved region that forms a tertiary structure beta-propeller. The gene that encodes KLHDC8A is located on chromosome 1, which is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6792R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6792R
Lokale Artikelnummer::
BOSSBS-6792R
Beschreibung:
The mammalian homologues of the key cell death gene CED 4 in C. elegans has been identified recently from human and mouse and designated Apaf1 (for apoptosis protease activating factor 1). Apaf1 binds to cytochrome c (Apaf2) and caspase 9 (Apaf3), which leads to caspase 9 activation. Activated caspase 9 in turn cleaves and activates caspase 3 that is one of the key proteases, being responsible for the proteolytic cleavage of many key proteins in apoptosis. A new Apaf1 Interacting Protein (APIP) also known as CG129 and MMRP19, has been identified as a negative regulator of ischemic injury. APIP competes with Caspase 9 binding site of Apaf1. APIP is predicted to code for a 204 amino acid. An isoform of APIP, APIP2 encodes a 242 amino acid protein, which is an alternative splicing variant differing in its N terminus from APIP. APIP transcript is ubiquitously expressed in most adult tissue with high expression in skeletal muscle, heart, and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7961R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7961R
Lokale Artikelnummer::
BOSSBS-7961R
Beschreibung:
Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 22–24 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases; most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7961R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7961R-CY7
Lokale Artikelnummer::
BOSSBS-7961R-CY7
Beschreibung:
Ankyrin is a membrane protein that mediates the attachment of the erythrocyte membrane skeleton to the plasma membrane and interacts with CD44 and inositol triphosphate. It contains three functional domains: a conserved N-terminal ankyrin repeat domain (ARD(consisting of 22–24 tandem repeats of 33 amino acids), a spectrin binding domain and a variably sized C-terminal regulatory domain. The ankyrin repeat is a 33-residue motif in proteins consisting of two alpha helices separated by loops. It has been studied using multiple sequence alignment to determine which conserved amino acid residues are critical for folding and stability. Ankyrin-repeat proteins have been associated with a number of human diseases; most notably, the cell cycle inhibitor p16 is associated with cancer and the Notch protein is a key component of cell signaling pathways whose intracellular repeat domain is disrupted in mutations that give rise to the neurological disorder known as CADASIL.
VE:
1 * 100 µl
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