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5-Brom-2-fluor-4-nitrotoluol
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5-Brom-2-fluor-4-nitrotoluol
Artikel-Nr:
(BOSSBS-5041R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5041R-A680
Lokale Artikelnummer::
BOSSBS-5041R-A680
Beschreibung:
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyses the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4937R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4937R-A350
Lokale Artikelnummer::
BOSSBS-4937R-A350
Beschreibung:
Cystatin A and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. Cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4172R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4172R-A647
Lokale Artikelnummer::
BOSSBS-4172R-A647
Beschreibung:
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-A750
Lokale Artikelnummer::
BOSSBS-13475R-A750
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2334R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2334R-A488
Lokale Artikelnummer::
BOSSBS-2334R-A488
Beschreibung:
Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and various plant metabolites, such as hyperforin, guggulipid, colupulone, and isoflavones. Response to specific ligands is species-specific. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12344R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12344R-A555
Lokale Artikelnummer::
BOSSBS-12344R-A555
Beschreibung:
FLVCR is responsible for the exportation of cytoplasmic heme groups. It is believed that it may protect developing erythroid cells from heme toxicity. Expression of FLVCR in cells will cause susceptibility to FeLV-C (Feline leukemia virus subgroup C) in vitro. FLVCR is found in all hematopoietic tissues, including peripheral blood lymphocytes and fetal liver, and some expression is found in pancreas and kidney. It is down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9513R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9513R-A680
Lokale Artikelnummer::
BOSSBS-9513R-A680
Beschreibung:
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesised in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1548R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1548R-A488
Lokale Artikelnummer::
BOSSBS-1548R-A488
Beschreibung:
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. recognises and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-20130R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-20130R-A750
Lokale Artikelnummer::
BOSSBS-20130R-A750
Beschreibung:
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9009R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9009R-A647
Lokale Artikelnummer::
BOSSBS-9009R-A647
Beschreibung:
Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0538R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0538R-A555
Lokale Artikelnummer::
BOSSBS-0538R-A555
Beschreibung:
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10228R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10228R-A680
Lokale Artikelnummer::
BOSSBS-10228R-A680
Beschreibung:
The protein encoded by this gene can hydrolyse substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumour suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4730R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4730R-A647
Lokale Artikelnummer::
BOSSBS-4730R-A647
Beschreibung:
Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12388R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12388R-A350
Lokale Artikelnummer::
BOSSBS-12388R-A350
Beschreibung:
KIF7 is a 1,343 amino acid protein expressed in embryonic stem cells, melanotic melanoma and Jurkat T-cells. KIF7 is a member of the KIF27 subfamily of the kinesin-like protein family and contains one kinesin-motor domain. It is suggested that KIF7 may participate in the Hedgehog (Hh) signaling pathway by regulating the proteolysis and stability of GLI transcription factors. Hedgehog (Hh) signaling plays a critical role in embryonic development.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2454R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2454R-A488
Lokale Artikelnummer::
BOSSBS-2454R-A488
Beschreibung:
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4819R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4819R-A488
Lokale Artikelnummer::
BOSSBS-4819R-A488
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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