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4,4\'-Dimethoxydiphenylamin
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4,4\'-Dimethoxydiphenylamin
Artikel-Nr:
(BOSSBS-8339R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8339R-CY5
Lokale Artikelnummer::
BOSSBS-8339R-CY5
Beschreibung:
The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4’-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8277R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8277R-CY5.5
Lokale Artikelnummer::
BOSSBS-8277R-CY5.5
Beschreibung:
May be involved in neurite outgrowth.G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/action, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling, and are involved in many pathological conditions. GRIN3 (G protein-regulated inducer of neurite outgrowth 3), also known as GPRIN3, is a 776 amino acid protein that contains a C-terminal region which shares a high homology with GRIN2 and GRIN1, and may function in neurite outgrowth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8276R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8276R-A750
Lokale Artikelnummer::
BOSSBS-8276R-A750
Beschreibung:
G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/actions, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesise intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. GRIN2 (G protein-regulated inducer of neurite outgrowth 2), also known as GPRIN2, is a 458 amino acid protein that is expressed in cerebellum and is thought to play a role in neurite outgrowth. GRIN2 interacts with activated G?oand G?, and is encoded by a gene that maps to human chromosome 10q11.22.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13370R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13370R-CY3
Lokale Artikelnummer::
BOSSBS-13370R-CY3
Beschreibung:
The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2 metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.
Artikel-Nr:
(BOSSBS-13370R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13370R-FITC
Lokale Artikelnummer::
BOSSBS-13370R-FITC
Beschreibung:
The glycine cleavage system is comprised of AMT (known as Protein T), GCSH (known as Protein H), DLD (known as Protein L) and GLDC (known as Protein P), all of which work together to catalyze the cleavage and degradation of glycine. GLDC (glycine dehydrogenase ), also known as GCE, GCSP (glycine cleavage system P protein) or HYGN1, is a 1,020 amino acid protein that localizes to the mitochondria and belongs to the gcvP family. GLDC binds to glycine and enables the methylamine group from glycine to be transferred to the Protein T. GLDC exists as a homodimer and utilizes pyridoxal phosphate as a cofactor. Mutations in the gene encoding GLDC leads to nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE), an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE55376245-1L)
Lieferant:
Molekula
Hersteller-Artikelnummer::
55376245-1L
Lokale Artikelnummer::
MOLE55376245-1L
Beschreibung:
Cloning Buffer, TE-Puffer-Lösung (TRIS-EDTA-Puffer) pH 7,5
VE:
1 * 1 L
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(SIALT3038-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
T3038-1L
Lokale Artikelnummer::
SIALT3038-1L
Beschreibung:
Cloning Buffer, TRIS Pufferlösung pH 8,0 (1 mol/l)
VE:
1 * 1 L
Artikel-Nr:
(SIALT2663-1L)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
T2663-1L
Lokale Artikelnummer::
SIALT2663-1L
Beschreibung:
Cloning Buffer, TRIS Pufferlösung pH 7,4 (1 mol/l)
VE:
1 * 1 L
Lieferant:
Sigma-Aldrich
Beschreibung:
Cloning Buffer, TRIS Pufferlösung pH 7,8 (1 mol/l)
Artikel-Nr:
(BOSSBS-8339R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8339R-HRP
Lokale Artikelnummer::
BOSSBS-8339R-HRP
Beschreibung:
The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4’-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8276R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8276R-A555
Lokale Artikelnummer::
BOSSBS-8276R-A555
Beschreibung:
G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/actions, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. GRIN2 (G protein-regulated inducer of neurite outgrowth 2), also known as GPRIN2, is a 458 amino acid protein that is expressed in cerebellum and is thought to play a role in neurite outgrowth. GRIN2 interacts with activated G?oand G?, and is encoded by a gene that maps to human chromosome 10q11.22.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13253R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13253R-CY7
Lokale Artikelnummer::
BOSSBS-13253R-CY7
Beschreibung:
Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9519R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9519R-A750
Lokale Artikelnummer::
BOSSBS-9519R-A750
Beschreibung:
BPGM (2,3-bisphosphoglycerate mutase) is a 259 amino acid protein that belongs to the phosphoglycerate mutase family and exists as a homodimer that plays a crucial role in the regulation of hemoglobin oxygen. Specifically, BPGM catalyses the conversion of 3-D-glyceroyl phosphate to 2,3-bisD-glycerate (2,3-BPG), a reaction that is essential for controlling the concentration of 2,3-BPG within the cell. The gene encoding BPGM maps to human chromosome 7, which houses over 1000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localised to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Involvement in disease: Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD). A disease characterised by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8277R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8277R-A350
Lokale Artikelnummer::
BOSSBS-8277R-A350
Beschreibung:
May be involved in neurite outgrowth.G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface receptors that are involved in a multitude of physiological processes such as perception of sensory information, modulation of synaptic transmission, hormone release/action, regulation of cell contraction/migration and cell growth/differentiation. GPCRs interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers, such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling, and are involved in many pathological conditions. GRIN3 (G protein-regulated inducer of neurite outgrowth 3), also known as GPRIN3, is a 776 amino acid protein that contains a C-terminal region which shares a high homology with GRIN2 and GRIN1, and may function in neurite outgrowth.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11733R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11733R-HRP
Lokale Artikelnummer::
BOSSBS-11733R-HRP
Beschreibung:
Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases. They are protein tyrosine phosphatases that utilize inositol phospholipids, rather than phosphoproteins, as substrates. MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2. MTMR2 interacts with MTMR5, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization. Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), which is characterized by reduced nerve conduction velocities, focally folded myelin sheaths and demyelination. MTMR3 and MTMR4 can either interact with each other or self associate. MTMR6 regulates the activity of the calcium-activated potassium channel 3.1. MTMR9 regulates the activity of MTMR7 and MTMR8.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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