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5-Bromothiophen-2-amine,+N-BOC+protected
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5-Bromothiophen-2-amine,+N-BOC+protected
Artikel-Nr:
(BOSSBS-0738R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0738R-FITC
Lokale Artikelnummer::
BOSSBS-0738R-FITC
Beschreibung:
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0738R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0738R-A555
Lokale Artikelnummer::
BOSSBS-0738R-A555
Beschreibung:
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
VE:
1 * 100 µl
Lieferant:
ELMA SCHMIDBAUER
Beschreibung:
Elma Mutebox facilitates optimum cleaning, every time. It is hygienic, low-noise and environmentally friendly.
Artikel-Nr:
(BOSSBS-8589R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8589R-A555
Lokale Artikelnummer::
BOSSBS-8589R-A555
Beschreibung:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
VE:
1 * 100 µl
Lieferant:
ABEBA
Beschreibung:
ESD-Schuh aus Glattleder.
Artikel-Nr:
(H51973.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H51973.06
Lokale Artikelnummer::
ALFAH51973.06
Beschreibung:
Fmoc-L-homophenylalanine 95%
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-0029R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0029R-A750
Lokale Artikelnummer::
BOSSBS-0029R-A750
Beschreibung:
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
VE:
1 * 100 µl
Lieferant:
Cayman Chemical
Beschreibung:
Petunidin is an O-methylated anthocyanidin derived from delphinidin that imparts blue-red pigments to flowers, fruits, and red wine. Used to bind with and suppress the activity of focal adhesion kinase and to inhibit platelet-derived growth factor-induced aortic smooth muscle cell migration, which may confer a protective effect against atherosclerosis. Extracts from E. jambolana fruit, which is rich in anthocyanins including petunidin, have been used to suppress the proliferation of an HCT116 colon cancer cell line, as well as colon cancer stem cells.
Artikel-Nr:
(BOSSBS-0431R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0431R-A680
Lokale Artikelnummer::
BOSSBS-0431R-A680
Beschreibung:
Acts as decoy receptor for TNFSF11/RANKL and thereby Neutralises its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis. TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0431R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0431R-A350
Lokale Artikelnummer::
BOSSBS-0431R-A350
Beschreibung:
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis. TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-18539R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-18539R-A680
Lokale Artikelnummer::
BOSSBS-18539R-A680
Beschreibung:
Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7790R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7790R-A350
Lokale Artikelnummer::
BOSSBS-7790R-A350
Beschreibung:
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7790R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7790R-HRP
Lokale Artikelnummer::
BOSSBS-7790R-HRP
Beschreibung:
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12344R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12344R-A488
Lokale Artikelnummer::
BOSSBS-12344R-A488
Beschreibung:
FLVCR is responsible for the exportation of cytoplasmic heme groups. It is believed that it may protect developing erythroid cells from heme toxicity. Expression of FLVCR in cells will cause susceptibility to FeLV-C (Feline leukemia virus subgroup C) in vitro. FLVCR is found in all hematopoietic tissues, including peripheral blood lymphocytes and fetal liver, and some expression is found in pancreas and kidney. It is down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12344R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12344R-A647
Lokale Artikelnummer::
BOSSBS-12344R-A647
Beschreibung:
FLVCR is responsible for the exportation of cytoplasmic heme groups. It is believed that it may protect developing erythroid cells from heme toxicity. Expression of FLVCR in cells will cause susceptibility to FeLV-C (Feline leukemia virus subgroup C) in vitro. FLVCR is found in all hematopoietic tissues, including peripheral blood lymphocytes and fetal liver, and some expression is found in pancreas and kidney. It is down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization.
VE:
1 * 100 µl
Lieferant:
ELTEN
Beschreibung:
GORE-TEX performance comfort footwear.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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