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2-Trifluoromethyl+acrylonitrile


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Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3769R-A555
Lokale Artikelnummer:: BOSSBS-3769R-A555
Beschreibung:   Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:  1 * 100 µl
Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-3769R-HRP
Lokale Artikelnummer:: BOSSBS-3769R-HRP
Beschreibung:   Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:  1 * 100 µl

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11318R-A555
Lokale Artikelnummer:: BOSSBS-11318R-A555
Beschreibung:   The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).
VE:  1 * 100 µl

Lieferant:  OriGene
Hersteller-Artikelnummer:: TA320313
Lokale Artikelnummer:: ORIGTA320313
Beschreibung:   Anti-CSF1R Rat Polyclonal Antibody [clone: 12-3A3-1B10]
VE:  1 * 25 µG
Artikel-Nr: (BOSSBS-13508R-CY7)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-13508R-CY7
Lokale Artikelnummer:: BOSSBS-13508R-CY7
Beschreibung:   G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-11879R-CY3)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-11879R-CY3
Lokale Artikelnummer:: BOSSBS-11879R-CY3
Beschreibung:   The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
VE:  1 * 100 µl
Artikel-Nr: (BOSSBS-13508R-CY3)

Lieferant:  Bioss
Hersteller-Artikelnummer:: BS-13508R-CY3
Lokale Artikelnummer:: BOSSBS-13508R-CY3
Beschreibung:   G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
VE:  1 * 100 µl
Lieferant:  FLUOROCHEM
Beschreibung:   N-(8-Bromoctyl)phthalimid
Artikel-Nr: (MOLEM10123276)

Lieferant:  Molekula
Hersteller-Artikelnummer:: M10123276
Lokale Artikelnummer:: MOLEM10123276
Beschreibung:   Brenzcatechin
VE:  1 * 1 kg
Market Source Item This is a MarketSource item. Additional charges may apply

Lieferant:  BIOLEGEND INC
Hersteller-Artikelnummer:: 576909
Lokale Artikelnummer:: BLEG576909
Beschreibung:   ELISA Standard 4-Pack contains four vials of recombinant mouse IL-12/IL-23 p40 at >5 ng per vial. Recommended for ELISA application only. Standards are calibrated against a BioLegend Master Calibrator.
VE:  1 * 1 Pack.
Market Source Item This is a MarketSource item. Additional charges may apply
Lieferant:  Bernd Kraft
Beschreibung:   Ethylenglycol, reinst
Lieferant:  BIOLEGEND INC
Beschreibung:   Mouse recombinant IL-12 (p70) Sf9 cells
Artikel-Nr: (KRAE900654-215)

Lieferant:  KRAEMER MARTIN
Hersteller-Artikelnummer:: 900654-215
Lokale Artikelnummer:: KRAE900654-215
Beschreibung:   Propylenglycol
VE:  1 * 215 kg
Lieferant:  EPPENDORF
Beschreibung:   Rotordeckel für F-45-12-11, für MiniSpin/MiniSpin plus
Lieferant:  EHRENSTORFER
Hersteller-Artikelnummer:: XA12480000CY
Lokale Artikelnummer:: EHERXA12480000CY
Beschreibung:   Organic Standard, 1,2-Dichlorpropan 100 µg/ml in Cyclohexan, Packung: Glasflasche
VE:  1 * 1 mL
Artikel-Nr: (PROOHXC001)

Lieferant:  LGC Standards PROMOCHEM
Hersteller-Artikelnummer:: HXC001
Lokale Artikelnummer:: PROOHXC001
Beschreibung:   4-Chlorbrenzcatechin
VE:  1 * 1 g
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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