Bis(tetramethylene)fluoroformamidinium+hexafluorophosphate
Artikel-Nr:
(BOSSBS-11705R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11705R-CY5
Lokale Artikelnummer::
BOSSBS-11705R-CY5
Beschreibung:
AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumor suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), implicating a role for AIP1 fusion proteins in tumorigenesis.
VE:
1 * 100 µl
Lieferant:
Quantabio
Beschreibung:
Die cDNA synthese und PCR erfolgen im gleichen Tube, ohne zwischenzeitliche Öffnung. Die Sets sind auf eine maximale Effizienz und Spezifität der RT-PCR ausgelegt und ermöglichen eine eindeutige Koamplifikation von Transkripten mit wenigen Exemplaren in Gegenwart von High-Copy-Referenzgenen. Dadurch bieten die qScript™ Einschritt-qRT-PCR-Sets eine höhere Empfindlichkeit als andere handelsübliche qPCR-Reagenzien. Das qScript™ Einschritt-Mastermix maximiert die Aktivität sowohl der reversen Transkriptase als auch der PCR-Enzyme und minimiert gleichzeitig die Primer-Dimer-Bildung. Für hohe Spezifität sorgt die AccuStart™ Taq DNA-Polymerase, die von monoklonalen Antikörpern gebunden wird, um einen optimalen Hot-Start zu ermöglichen. Nach der Erwärmung auf 95 °C denaturieren die Antikörper irreversibel und setzen vollständig aktive und unveränderte Taq DNA-Polymerase frei. Die One Step qRT-PCR Kits sind für RTPCR Geräte, inklusive Geräten, welche einen normalisierten ROX Farbstoff benötigen, verfügbar.
Lieferant:
Alfa Aesar
Beschreibung:
7-Amino-4-(trifluormethyl)cumarin 99%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Methoxy-1-indanon 98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
3-Acetyl-5-bromo-1H-indazole 96%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Chloro-3-(trifluoromethyl)phenacyl bromide
Artikel-Nr:
(PROOMM0609.07)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
MM0609.07
Lokale Artikelnummer::
PROOMM0609.07
Beschreibung:
Organic Standard, 5-(1-Methylpiperidin-4-yl)-5H-dibenzo[a,d][7]annulen-5-ol hydrochloride
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-13084R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R
Lokale Artikelnummer::
BOSSBS-13084R
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11489R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11489R-HRP
Lokale Artikelnummer::
BOSSBS-11489R-HRP
Beschreibung:
TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11726R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11726R-A488
Lokale Artikelnummer::
BOSSBS-11726R-A488
Beschreibung:
Hexosaminidase A (HEXA), also designated beta-Hexosaminidase A, is a trimer composed of one å chain, one ∫-A chain and one ∫-B chain and is found in the lysosomes of cells. HEXA, along with the cofactor CM2 activator protein, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues. A mutation in the å subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13084R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13084R-A647
Lokale Artikelnummer::
BOSSBS-13084R-A647
Beschreibung:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11489R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11489R-CY7
Lokale Artikelnummer::
BOSSBS-11489R-CY7
Beschreibung:
TNRC6B is a 1,723 amino acid protein that exists as two alternatively spliced isoforms and is thought to be involved in mRNA cleavage events. Expressed ubiquitously, TNRC6B contains one glycine/tryptophan (GW)-rich N-terminal domain, one central glutamine-rich region and one C-terminal RNA recognition motif and is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4819R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4819R
Lokale Artikelnummer::
BOSSBS-4819R
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4819R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4819R-A750
Lokale Artikelnummer::
BOSSBS-4819R-A750
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2617R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2617R-A647
Lokale Artikelnummer::
BOSSBS-2617R-A647
Beschreibung:
Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1-(tert-Butoxycarbonyl)-3,3-dimethyl-4-oxopiperidine 95%
Preis auf Anfrage
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