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Methyl+7-methoxyindole-5-carboxylate
Artikel-Nr:
(BOSSBS-9156R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9156R-A750
Lokale Artikelnummer::
BOSSBS-9156R-A750
Beschreibung:
SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9156R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9156R-CY7
Lokale Artikelnummer::
BOSSBS-9156R-CY7
Beschreibung:
SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9156R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9156R-FITC
Lokale Artikelnummer::
BOSSBS-9156R-FITC
Beschreibung:
SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2835R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2835R-FITC
Lokale Artikelnummer::
BOSSBS-2835R-FITC
Beschreibung:
The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
VE:
1 * 100 µl
Artikel-Nr:
(SMEGGW0160-1)
Lieferant:
SMEG
Hersteller-Artikelnummer::
GW0160-1
Lokale Artikelnummer::
SMEGGW0160-1
Beschreibung:
Mehrzweck-Reinigungsautomat für den professionellen Einsatz, mit Waschtemperaturen von bis zu 85 °C (thermale Desinfektion) und Peristaltikpumpen zur Dosierung von Flüssigreiniger und Neutralisationsmittel. Dieser Reinigungsautomat eignet sich perfekt für die Reinigung und Desinfektion aller Arten von Instrumenten, die in kleinen Labors, Universitäten, Schulen, Spezialkliniken, Tätowierstudios, tierärztlichen Kliniken und vielen weiteren Umgebungen eingesetzt werden.
VE:
1 * 1 ST
Artikel-Nr:
(EHERC12965400)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C12965400
Lokale Artikelnummer::
EHERC12965400
Beschreibung:
Kongorot
VE:
1 * 0,1 g
Artikel-Nr:
(620-1553)
Lieferant:
EBRO
Hersteller-Artikelnummer::
1340-1786
Lokale Artikelnummer::
EBRO1340-1786
Beschreibung:
Infrarotthermometer für Messungen, bei denen ein direkter Kontakt nicht möglich oder unpraktisch ist. Mit NiCr-Ni-Anschluss.
VE:
1 * 1 ST
Artikel-Nr:
(MOLEM31475505)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M31475505
Lokale Artikelnummer::
MOLEM31475505
Beschreibung:
Brillantgrün (Malachitgrün G)
VE:
1 * 100 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
MAPA
Beschreibung:
Diese Handschuhe für schwere Arbeiten sind im Bereich der Innenhand mit einer Lederschicht und an Daumen/Zeigefinger mit einer Verstärkung ausgestattet, was für einen guten Schutz beim Umgang mit schweren und scharfkantigen Metallteilen sowohl in trockenen als auch in leicht feuchten Umgebungen sorgt. Mit nahtlosem Textilfutter aus hochstabilen Fasern.
Artikel-Nr:
(MOLE42186946-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
42186946-25G
Lokale Artikelnummer::
MOLE42186946-25G
Beschreibung:
Safranin O
VE:
1 * 25 g
This is a MarketSource item. Additional charges may apply
Lieferant:
VWR Collection
Beschreibung:
Hydrophobes Filterpapier für die Trennung wässriger und organischer Lösungen.
Artikel-Nr:
(BOSSBS-11242R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11242R-FITC
Lokale Artikelnummer::
BOSSBS-11242R-FITC
Beschreibung:
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11242R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11242R-A488
Lokale Artikelnummer::
BOSSBS-11242R-A488
Beschreibung:
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11333R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11333R-A680
Lokale Artikelnummer::
BOSSBS-11333R-A680
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with Clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of Clathrin binding Adaptin proteins (g and b1 for AP-1, a and b2 for AP-2) and two smaller subunits known as AP50 and AP17. The a and b Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. a-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP-3 (also designated AP180 or F1-20) is a synapse-specific Clathrin assembly protein. The protein CALM (Clathrin assembly protein lymphoid myeloid leukaemia) is highly homologous to AP180 and may also be involved in Clathrin assembly.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9156R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9156R-HRP
Lokale Artikelnummer::
BOSSBS-9156R-HRP
Beschreibung:
SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11884R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11884R-A350
Lokale Artikelnummer::
BOSSBS-11884R-A350
Beschreibung:
The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in adults. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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