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5-Fluor-2-benzo[b]thiophencarbonsäure
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5-Fluor-2-benzo[b]thiophencarbonsäure
Artikel-Nr:
(BOSSBS-5334R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5334R-A488
Lokale Artikelnummer::
BOSSBS-5334R-A488
Beschreibung:
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5736R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5736R-A647
Lokale Artikelnummer::
BOSSBS-5736R-A647
Beschreibung:
TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7786R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7786R-A647
Lokale Artikelnummer::
BOSSBS-7786R-A647
Beschreibung:
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2498R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2498R-A488
Lokale Artikelnummer::
BOSSBS-2498R-A488
Beschreibung:
Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3864R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3864R-A680
Lokale Artikelnummer::
BOSSBS-3864R-A680
Beschreibung:
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6236R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6236R-A680
Lokale Artikelnummer::
BOSSBS-6236R-A680
Beschreibung:
This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6007R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6007R-A680
Lokale Artikelnummer::
BOSSBS-6007R-A680
Beschreibung:
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterised by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6240R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6240R-A350
Lokale Artikelnummer::
BOSSBS-6240R-A350
Beschreibung:
TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5515R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5515R-A647
Lokale Artikelnummer::
BOSSBS-5515R-A647
Beschreibung:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6763R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6763R-A350
Lokale Artikelnummer::
BOSSBS-6763R-A350
Beschreibung:
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15497R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15497R-A750
Lokale Artikelnummer::
BOSSBS-15497R-A750
Beschreibung:
DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13681R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13681R-A647
Lokale Artikelnummer::
BOSSBS-13681R-A647
Beschreibung:
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6240R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6240R-A555
Lokale Artikelnummer::
BOSSBS-6240R-A555
Beschreibung:
TLX3 (HOX11L2, RNX) belongs to a family of orphan homeobox genes that encode DNA binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine 47 replacing cytosine in the highly conserved homeodomain. This transcription factor is required for hematopoiesis. It is overexpressed in childhood acute lumphoblastic leukemia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7709R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7709R-A647
Lokale Artikelnummer::
BOSSBS-7709R-A647
Beschreibung:
Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.Tissue specificity:Expressed most abundantly in ovary and, at lower levels, in prostate, spleen and testis. Weak expression, if any, in thymus, small intestine, colon and peripheral blood leukocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12242R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12242R-A350
Lokale Artikelnummer::
BOSSBS-12242R-A350
Beschreibung:
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6177R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6177R-A647
Lokale Artikelnummer::
BOSSBS-6177R-A647
Beschreibung:
RAB proteins are GTPases that regulate vesicular trafficking and reside in specific intracellular compartments. RAB9 has been localized to components of the endocytic/exocytic pathway. It has been implicated in the recycling of membrane receptors, such as the mannose 6-phosphate receptor from early endosomes to the trans Golgi network.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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