5-Fluor-2-benzo[b]thiophencarbonsäure
Artikel-Nr:
(BOSSBS-12222R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12222R-A350
Lokale Artikelnummer::
BOSSBS-12222R-A350
Beschreibung:
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development. [provided by RefSeq, Oct 2012].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0646R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0646R-A680
Lokale Artikelnummer::
BOSSBS-0646R-A680
Beschreibung:
Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6536R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6536R-A750
Lokale Artikelnummer::
BOSSBS-6536R-A750
Beschreibung:
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7000R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7000R-A647
Lokale Artikelnummer::
BOSSBS-7000R-A647
Beschreibung:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1595R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1595R-A350
Lokale Artikelnummer::
BOSSBS-1595R-A350
Beschreibung:
spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11309R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11309R-A680
Lokale Artikelnummer::
BOSSBS-11309R-A680
Beschreibung:
The testis spermatocyte apoptosis-related gene 2 protein (TSARG2, also designated spermatogenesis associated-4 or SPATA4) is involved in spermatogenesis. TSARG2 is specifically expressed in spermatogonia and spermatocytes of the seminiferous tubules, and it localizes to the nucleus. The predicted molecular weight of TSARG2 ranges depending on the species. TSARG2 is significantly upregulated in cryptorchidism and therefore, is a testis-specific apoptosis candidate oncogene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4905R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4905R-A680
Lokale Artikelnummer::
BOSSBS-4905R-A680
Beschreibung:
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3513R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3513R-A647
Lokale Artikelnummer::
BOSSBS-3513R-A647
Beschreibung:
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5009R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5009R-A647
Lokale Artikelnummer::
BOSSBS-5009R-A647
Beschreibung:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5009R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5009R-A555
Lokale Artikelnummer::
BOSSBS-5009R-A555
Beschreibung:
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. The two calmodulin-binding domains appear to act in concert to bind a single molecule of calmodulin and are pseudosubstrate/autoinhibitory domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0787R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0787R-A555
Lokale Artikelnummer::
BOSSBS-0787R-A555
Beschreibung:
Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â… molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3873R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3873R-A750
Lokale Artikelnummer::
BOSSBS-3873R-A750
Beschreibung:
ATG4A is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4962R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4962R-A647
Lokale Artikelnummer::
BOSSBS-4962R-A647
Beschreibung:
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4839R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4839R-A350
Lokale Artikelnummer::
BOSSBS-4839R-A350
Beschreibung:
Influenza A and B are the two types of influenza viruses that cause epidemic human disease. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Influenza A viruses are further categorized into subtypes on the basis of two surface antigens: hemagglutinin (H) and neuraminidase (N). Strains are also described by geographic origin, strain number and year of isolation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7000R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7000R-A350
Lokale Artikelnummer::
BOSSBS-7000R-A350
Beschreibung:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6558R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6558R-A350
Lokale Artikelnummer::
BOSSBS-6558R-A350
Beschreibung:
May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
VE:
1 * 100 µl
Preis auf Anfrage
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