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6-Bromo-2-hydrazino-3-methylquinoline+hydrochloride
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6-Bromo-2-hydrazino-3-methylquinoline+hydrochloride
Artikel-Nr:
(BOSSBS-6578R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6578R-A750
Lokale Artikelnummer::
BOSSBS-6578R-A750
Beschreibung:
The sterile alpha motif (SAM) domain is a 70 residue structure found in a large number of proteins involved in diverse processes present throughout eukaryotes. The SAM domain is known to bind RNA and is arranged in a small five-helix bundle with two large interfaces. SAMD14 (sterile alpha motif domain-containing protein 14) is a 417 amino acid protein encoded by the SAMD14 gene which maps to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Chromosome 17 is also linked to neurofibromatosis, a condition characterised by neural and epidermal lesions, and dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5217R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5217R-CY5.5
Lokale Artikelnummer::
BOSSBS-5217R-CY5.5
Beschreibung:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5219R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5219R-A680
Lokale Artikelnummer::
BOSSBS-5219R-A680
Beschreibung:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15573R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15573R-A555
Lokale Artikelnummer::
BOSSBS-15573R-A555
Beschreibung:
Ig delta chain C region is an allelic product of the human IGHD gene. The two known IGHD alleles, IGHD*01 and IGHD*02, respectively produce isoforms 1, a secreted protein, and 2, a single-pass type I membrane protein. A member of the adaptive immune system, IgD are monomers expressed by activated B cells. Containing 3 Ig-like (immunoglobulin-like) domains, IgD chain C is located on chromosome 14 within the human heavy chain locus, lying on the 3? side of the IgM chain C region from the V-D-J cassette. Polyadenylation at certain sites along the heavy chain locus likely effects the mechanism that determines the alternative splicing event which results in the expression of either IgD chain C or IgM chain C. Some studies have suggested that antigenic coactivation of IgD+ B cells can have a negative influence on bone resorption during infectious events.
VE:
1 * 100 µl
Lieferant:
DWK Life Sciences
Beschreibung:
EPDM Kautschuk.
Lieferant:
Sigma-Aldrich
Beschreibung:
4-Amino-N,N-dimethylanilin, Sigma-Aldrich®
Artikel-Nr:
(BLEG104443)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
104443
Lokale Artikelnummer::
BLEG104443
Beschreibung:
Anti-CD62L Rat Monoclonal Antibody [clone: MEL-14]
VE:
1 * 100 µG
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(SCOT257520107)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
257520107
Lokale Artikelnummer::
SCOT257520107
Beschreibung:
Aufsatz für 100 ml Gaswaschflasche, mit NS 34/35, DURAN®, Kapazität: 250 ml
VE:
1 * 1 ST
Lieferant:
Hach
Beschreibung:
Test kit, Chlorine (free) DPD, Messbereich: 0 - 3,5 mg/l
Artikel-Nr:
(ABNOMAB2192)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB2192
Lokale Artikelnummer::
ABNOMAB2192
Beschreibung:
Hamster monoclonal antibody raised against recombinant Bcl3.
VE:
1 * 100 µG
Lieferant:
SciLabware
Beschreibung:
PYREX®, Borosilikatglas.
Lieferant:
Merck Millipore (Calbiochem)
Beschreibung:
Spotolysin reagent is a concentrated solution of Dithiothreitol in phosphate buffer. Mainly for the isolation of epithelial cells, pathogenic or saprophytic bacteria, fungi, and yeasts from sputum.
Artikel-Nr:
(SIALC7727-500MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
C7727-500MG
Lokale Artikelnummer::
SIALC7727-500MG
Beschreibung:
Curcumin, Sigma-Aldrich®
VE:
1 * 500 mg
Artikel-Nr:
(BOSSBS-13235R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13235R
Lokale Artikelnummer::
BOSSBS-13235R
Beschreibung:
This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, FXYD7, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu., Dec 2000].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13234R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13234R-CY3
Lokale Artikelnummer::
BOSSBS-13234R-CY3
Beschreibung:
The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids. Members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, mammary tumor protein), FXYD4 (CHIF) and FXYD5 (RIC). FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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