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2-(4-Isobutylphenyl)acetic+acid
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2-(4-Isobutylphenyl)acetic+acid
Artikel-Nr:
(BOSSBS-13123R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13123R-A350
Lokale Artikelnummer::
BOSSBS-13123R-A350
Beschreibung:
EXTL3 is a member of the EXT (hereditary multiple exostosin) gene family of tumor suppressors encoding glycosyltransferases involved in heparan sulfate (HS) biosynthesis. Within this family, the C-terminus is conserved between all members from C. elegans to vertebrates. EXTL3 is a ubiquitously expressed, developmentally regulated, single-pass type II membrane protein that localizes to the endoplasmic reticulum membrane. EXTL3 adds N-acetylglucosamine (GlcNAc) to the polysaccharide-protein linkage region and to the growing HS chain suggesting that it plays a role in both the initiation and elongation of HS chains. In addition, EXTL3 may act as a Reg receptor, binding Reg via its N-terminus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3872R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3872R-CY5.5
Lokale Artikelnummer::
BOSSBS-3872R-CY5.5
Beschreibung:
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2751R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2751R-CY5
Lokale Artikelnummer::
BOSSBS-2751R-CY5
Beschreibung:
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1501R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1501R-HRP
Lokale Artikelnummer::
BOSSBS-1501R-HRP
Beschreibung:
This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1424R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1424R-A555
Lokale Artikelnummer::
BOSSBS-1424R-A555
Beschreibung:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4037R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4037R-FITC
Lokale Artikelnummer::
BOSSBS-4037R-FITC
Beschreibung:
SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2963R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2963R-CY5.5
Lokale Artikelnummer::
BOSSBS-2963R-CY5.5
Beschreibung:
This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4632R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4632R
Lokale Artikelnummer::
BOSSBS-4632R
Beschreibung:
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9077R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9077R
Lokale Artikelnummer::
BOSSBS-9077R
Beschreibung:
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Specifically, Cdk2 interacts with Cyclins A, B1, B3, D, or E to control cell cycle progression. The Cyclin-dependent kinase 2-interacting protein (CINP) interacts with components of the replication complex and Cdk2 and Cdc7, thereby providing a functional and physical link between Cdk2 and Cdc7 during firing of the origins of replication. However, CINP is phopshorylated by Cdc7, but not by Cdk2. CINP also interacts with ATR-interacting protein and regulates ATR-dependent signaling, resistance to replication stress and G2 checkpoint integrity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6925R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6925R-CY5.5
Lokale Artikelnummer::
BOSSBS-6925R-CY5.5
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC51 (coiled-coil domain containing 51) is a 411 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding CCDC51 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2571R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2571R-FITC
Lokale Artikelnummer::
BOSSBS-2571R-FITC
Beschreibung:
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3764R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3764R-A555
Lokale Artikelnummer::
BOSSBS-3764R-A555
Beschreibung:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6336R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6336R-HRP
Lokale Artikelnummer::
BOSSBS-6336R-HRP
Beschreibung:
APOB48R is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. It may provide essential lipids, lipid soluble vitamins and other nutrients to reticuloendothelial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4235R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4235R-CY5
Lokale Artikelnummer::
BOSSBS-4235R-CY5
Beschreibung:
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4815R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4815R-HRP
Lokale Artikelnummer::
BOSSBS-4815R-HRP
Beschreibung:
The CD3 complex mediates signal transduction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11053R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11053R-FITC
Lokale Artikelnummer::
BOSSBS-11053R-FITC
Beschreibung:
May be an adhesion-like molecule with anti-protease activity.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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