5-Carboxy-2-fluorphenylborons\u00E4ure
Artikel-Nr:
(BOSSBS-11408R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11408R-A750
Lokale Artikelnummer::
BOSSBS-11408R-A750
Beschreibung:
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0744R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0744R-A488
Lokale Artikelnummer::
BOSSBS-0744R-A488
Beschreibung:
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is a highly glycosylated protein expressed only in neutrophils and eosinophils in humans. The precise function of CEACAM8 remains unclear. As a member of the family of carcinoembryonic antigen (CEA), it may play a role in the interaction between granulocytes or between granulocytes and epithelial cells. Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6518R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6518R-A350
Lokale Artikelnummer::
BOSSBS-6518R-A350
Beschreibung:
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4820R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4820R-A647
Lokale Artikelnummer::
BOSSBS-4820R-A647
Beschreibung:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5975R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5975R-A350
Lokale Artikelnummer::
BOSSBS-5975R-A350
Beschreibung:
SSX8 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2885R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2885R-A680
Lokale Artikelnummer::
BOSSBS-2885R-A680
Beschreibung:
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6938R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6938R-A555
Lokale Artikelnummer::
BOSSBS-6938R-A555
Beschreibung:
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is the one EBV antigen that is expressed in all EBV associated malignancies. It has long been thought to go undetected by the cell mediated immune system. However, recent studies show that EBNA1 can be presented to both CD4+ and CD8+ T cells, making it a potential new target for immunotherapy of EBV related cancers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2540R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2540R-A350
Lokale Artikelnummer::
BOSSBS-2540R-A350
Beschreibung:
GLUT12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9352R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9352R-A350
Lokale Artikelnummer::
BOSSBS-9352R-A350
Beschreibung:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Binds to the C-terminus of CDKN1A and thereby mediates its degradation. Negatively regulates the membrane trafficking of the cell-surface thromboxane A2 receptor (TBXA2R) isoform 2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8511R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8511R-A555
Lokale Artikelnummer::
BOSSBS-8511R-A555
Beschreibung:
Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3822R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3822R-A350
Lokale Artikelnummer::
BOSSBS-3822R-A350
Beschreibung:
Cyclin G2 may play a role in growth regulation and in negative regulation of cell cycle progesssion. Cyclin G2 expression levels increase through the cell cycle to peak in the mid/late-S phase and decrease during G2/M phase. It may also contribute in maintaining the quiescent state of differentiated cells. Cyclin G2 is similar to cyclin A in the cyclin box, although no kinase activity is detected.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0179R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0179R-A680
Lokale Artikelnummer::
BOSSBS-0179R-A680
Beschreibung:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6976R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6976R-A488
Lokale Artikelnummer::
BOSSBS-6976R-A488
Beschreibung:
Phospholipase C beta 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Its gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for its gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7583R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7583R-A350
Lokale Artikelnummer::
BOSSBS-7583R-A350
Beschreibung:
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8164R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8164R-A555
Lokale Artikelnummer::
BOSSBS-8164R-A555
Beschreibung:
FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11825R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11825R-A555
Lokale Artikelnummer::
BOSSBS-11825R-A555
Beschreibung:
DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.
VE:
1 * 100 µl
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