6-Fluorobenzo[d]isoxazol-3(2H)-one
Artikel-Nr:
(BOSSBS-6236R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6236R-CY5.5
Lokale Artikelnummer::
BOSSBS-6236R-CY5.5
Beschreibung:
This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
2'-Brom-4'-fluoracetophenon ≥98%
Lieferant:
Thermo Scientific
Beschreibung:
Aceton-[D6] 99.5 atom % D + 1% TMS für die Kernresonanzspektroskopie
Artikel-Nr:
(BOSSBS-4289R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4289R-A555
Lokale Artikelnummer::
BOSSBS-4289R-A555
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11446R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11446R-FITC
Lokale Artikelnummer::
BOSSBS-11446R-FITC
Beschreibung:
BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.4). It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
Artikel-Nr:
(BOSSBS-11446R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11446R-HRP
Lokale Artikelnummer::
BOSSBS-11446R-HRP
Beschreibung:
BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11641R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11641R-A647
Lokale Artikelnummer::
BOSSBS-11641R-A647
Beschreibung:
BPTF is a 2,907 amino acid protein encoded by the human gene BPTF. BPTF belongs to the PBTF family and contains one bromodomain, one DDT domain and two PHD-type zinc fingers. BPTF acts as a histone-binding component of NURF (nucleosome-remodeling factor). The NURF complex, which consists of SMARCA1, BPTF, RbAp46 and RbAp48, acts to catalyze ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It specifically recognizes histone H3 tails trimethylated on 'Lys-4' (H3-K4Me3), which mark transcription start sites of virtually all active genes. BPTF may also help regulate transcription through direct binding to DNA or transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11641R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11641R-A680
Lokale Artikelnummer::
BOSSBS-11641R-A680
Beschreibung:
BPTF is a 2907 amino acid protein encoded by the human gene BPTF. BPTF belongs to the PBTF family and contains one bromodomain, one DDT domain and two PHD-type zinc fingers. BPTF acts as a histone-binding component of NURF (nucleosome-remodeling factor). The NURF complex, which consists of SMARCA1, BPTF, RbAp46 and RbAp48, acts to catalyse ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It specifically recognizes histone H3 tails trimethylated on 'Lys-4' (H3-K4Me3), which mark transcription start sites of virtually all active genes. BPTF may also help regulate transcription through direct binding to DNA or transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6015R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6015R-A647
Lokale Artikelnummer::
BOSSBS-6015R-A647
Beschreibung:
SNF2L, also known as SMARCA1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1), SWI or ISWI, is a 1,054 amino acid protein that localizes to the nucleus and contains one helicase C-terminal domain, one helicase ATP-binding domain and two SANT domains. Expressed as multiple alternatively spliced isoforms, SNF2L exists as a component of the nucleosome-remodeling factor (NURF) complex where it helps to facilitate the ATP-dependent perturbation of chromatin structure and may also be involved in brain development and neurite outgrowth. The gene encoding SNF2L maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11087R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11087R-A488
Lokale Artikelnummer::
BOSSBS-11087R-A488
Beschreibung:
LRFN2 is a 789 amino acid single-pass type I membrane protein belonging to the LRFN family. Encoded by a gene that maps to human chromosome 6p21.2, LRFN2 is moderately expressed in brain, spleen and testis. LRFN2 contains one fibronectin type-III domain, one Ig-like (immunoglobulin-like) domain and six LRR (leucine-rich) repeats. LRFN2 promotes neurite outgrowth in hippocampal neurons, enhances cell surface expression of two NMDA receptor subunits, NMDAΩ1 and NMDAé1, and may play a role in redistributing PSD-95 to cell periphery. LRFN2 forms heteromeric complexes with LRFN1, LRFN3, LRFN4 and LRFN5, and is capable of forming homomeric complexes, but not across cell junctions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12051R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12051R
Lokale Artikelnummer::
BOSSBS-12051R
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD223375-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD223375-100MG
Lokale Artikelnummer::
BLDPBD223375-100MG
Beschreibung:
1'-Boc-1,2-dihydro-2-oxospiro[3H-indole-3,4'-piperidine] 97%
VE:
1 * 100 mg
Lieferant:
Alfa Aesar
Beschreibung:
2'-Fluor-4'-hydroxyacetophenon ≥97%
Artikel-Nr:
(BOSSBS-13496R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13496R
Lokale Artikelnummer::
BOSSBS-13496R
Beschreibung:
Glycosylphosphatidylinositol (GPI) acts as a membrane anchor for cell surface proteins. Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), also designated GPI anchor attachment protein 1 or GAA1 protein homolog, is a membrane protein localized to the endoplasmic reticulum which is involved in GPI-anchor biosynthesis. GPAA1 is crucial for GPI-anchoring of precursor proteins and catalyzes the attachment of GPI to proteins containing a C-terminal GPR attachment signal. GAA1 contains an N-terminal signal sequence, one cAMP- and cGMP-dependent protein kinase phosphorylation site, two potential N-glycosylation sites, one leucine zipper pattern and eight putative transmembrane domains. GPAA1 is ubiquitously expressed and shows higher levels of expression in fetal tissues than in adult tissues.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11229R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11229R
Lokale Artikelnummer::
BOSSBS-11229R
Beschreibung:
OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases. Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, thereby preventing protein degradation and playing an important role in protein turnover. OTUB1 interacts with GRAIL and, via this interaction, plays a role in the regulation and the induction of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens. Due to its interaction with GRAIL, OTUB1 is an important regulator of immune responses in secondary lymphoid organs.
VE:
1 * 100 µl
Preis auf Anfrage
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