3-(4-Fluorophenyl)oxetan-3-ol
Artikel-Nr:
(BOSSBS-1910R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1910R-CY7
Lokale Artikelnummer::
BOSSBS-1910R-CY7
Beschreibung:
Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. There are 3 forms encoded by separate genes TGFB1, TGFB2, and TGFB3. The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins. In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), type III (TGF beta III receptor) has been identified. It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form. It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems. TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling. Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration. Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2. These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, nonredundant role in TGF beta signaling. TGF beta III receptor, or beta glycan, can function as an inhibin coreceptor with ActRII. TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor. Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII. TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone.
VE:
1 * 100 µl
Artikel-Nr:
(DG016)
Lieferant:
G-Biosciences
Hersteller-Artikelnummer::
DG016
Lokale Artikelnummer::
GENODG016
Beschreibung:
N-Octyl-β-D-glucopyranosid
VE:
1 * 5 g
Artikel-Nr:
(JACK109-025-098)
Lieferant:
Jackson Immuno Research
Hersteller-Artikelnummer::
109-025-098
Lokale Artikelnummer::
JACK109-025-098
Beschreibung:
Anti-IgG F(c) gamma Goat Polyclonal Antibody (TRITC (Tetramethylrhodamine Isothiocyanate))
VE:
1 * 1 mg
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Artikel-Nr:
(USBIC1035-25Q4)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C1035-25Q4
Lokale Artikelnummer::
USBIC1035-25Q4
Beschreibung:
Anti-Calmodulin-Dependent Protein Kinase II beta Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(USBIP4186-28C-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P4186-28C-PE
Lokale Artikelnummer::
USBIP4186-28C-PE
Beschreibung:
Anti-PI 4 Kinase Type 2 beta Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBIP9107-17F-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9107-17F-FITC
Lokale Artikelnummer::
USBIP9107-17F-FITC
Beschreibung:
Anti-Protein Phosphatase 1 beta Rabbit Polyclonal Antibody (FITC (Fluorescein))
VE:
1 * 200 µl
Artikel-Nr:
(USBII7661-26H1)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I7661-26H1
Lokale Artikelnummer::
USBII7661-26H1
Beschreibung:
Anti-Insulin Receptor, beta Mouse Monoclonal Antibody [clone: 5J296]
VE:
1 * 100 µG
Artikel-Nr:
(USBIP9102-91K4-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9102-91K4-AP
Lokale Artikelnummer::
USBIP9102-91K4-AP
Beschreibung:
Anti-PKA C-beta Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIN2565-32B)
Lieferant:
US Biological
Hersteller-Artikelnummer::
N2565-32B
Lokale Artikelnummer::
USBIN2565-32B
Beschreibung:
Anti-Nicotinic Receptor, beta 3 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0100R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0100R-CY7
Lokale Artikelnummer::
BOSSBS-0100R-CY7
Beschreibung:
Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0100R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0100R-FITC
Lokale Artikelnummer::
BOSSBS-0100R-FITC
Beschreibung:
Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4511R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4511R-A680
Lokale Artikelnummer::
BOSSBS-4511R-A680
Beschreibung:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4511R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4511R-A750
Lokale Artikelnummer::
BOSSBS-4511R-A750
Beschreibung:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1546R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1546R-CY7
Lokale Artikelnummer::
BOSSBS-1546R-CY7
Beschreibung:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1546R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1546R-CY3
Lokale Artikelnummer::
BOSSBS-1546R-CY3
Beschreibung:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
VE:
1 * 100 µl
Artikel-Nr:
(USBIH1834-55V)
Lieferant:
US Biological
Hersteller-Artikelnummer::
H1834-55V
Lokale Artikelnummer::
USBIH1834-55V
Beschreibung:
Anti-Heat Shock Protein 90, beta Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Preis auf Anfrage
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