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5-Oxaspiro[3.5]nonan-8-one
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5-Oxaspiro[3.5]nonan-8-one
Artikel-Nr:
(BOSSBS-6592R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6592R-A555
Lokale Artikelnummer::
BOSSBS-6592R-A555
Beschreibung:
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.Tissue specificity; Detected in liver and prostate (at protein level). Detected in adult liver, lung, brain, placenta, prostate, adrenal gland, testis, mammary gland, spleen, spinal cord and uterus. Detected in caudate nucleus, and at lower levels in amygdala, corpus callosum, hippocampus, substantia nigra and thalamus. Detected in fetal lung, liver and brain.Sequence similarities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7736R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7736R-CY5
Lokale Artikelnummer::
BOSSBS-7736R-CY5
Beschreibung:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
VE:
1 * 100 µl
Lieferant:
FRISTADS KANSAS
Beschreibung:
Robust trousers for ladies, made from 65% polyester and 35% cotton, with soft nap on reverse side.
Artikel-Nr:
(MOLEM55267000)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M55267000
Lokale Artikelnummer::
MOLEM55267000
Beschreibung:
3-(Trifluormethyl)zimtsäure
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-13343R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-A647
Lokale Artikelnummer::
BOSSBS-13343R-A647
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7736R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7736R-A647
Lokale Artikelnummer::
BOSSBS-7736R-A647
Beschreibung:
Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13343R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13343R-CY3
Lokale Artikelnummer::
BOSSBS-13343R-CY3
Beschreibung:
The GGA family of proteins (Golgi-localized, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin (1?). Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1,2,4). GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, and STAM) domain followed by a GAT (GGA and TOM1) domain, a connecting hinge segment, and a C-terminal GAE (?adaptin ear) domain (5). The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3). GGA1 and GGA2 do not associate with each other, but they do colocalize on perinuclear membranes (2). The cytosolic domain of memapsin 2, but not that of memapsin 1, binds the VHS domains of GGA1 and GGA2 (6). The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1).
VE:
1 * 100 µl
Artikel-Nr:
(PIER20504)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
20504
Lokale Artikelnummer::
PIER20504
Beschreibung:
Thermo Scientific Pierce Sodium meta-Periodate is a gentle oxidizing agent that cleaves cis-diols in carbohydrate sugars to create amine-reactive aldehydes, providing many uses relating to the study and detection of glycoproteins.
VE:
1 * 25 g
Lieferant:
Hach
Beschreibung:
Diese Pipetten sind handliche Mikroliterpipetten für allgemeine Anwendungen, z.B. zum Transferieren von exakten Flüssigkeitsvolumen. Die Funktionsweise basiert auf dem Luftpolster-Prinzip mit Einweg-Spitzen. Das Volumen wir klar und eindeutig auf der Anzeige auf dem Pipettengriff angezeigt.
Lieferant:
SIGMA ALDRICH MICROSCOPY
Beschreibung:
Brilliant Blue G has been used for determining the urine protein concentration. It has been used for the protein band detection after SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). It has been used as a P2X7R (purinergic receptor) antagonist.
Artikel-Nr:
(EHERC10934700)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
C10934700
Lokale Artikelnummer::
EHERC10934700
Beschreibung:
Kaffeesäure
VE:
1 * 0,1 g
Artikel-Nr:
(PRSI29-527)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
29-527
Lokale Artikelnummer::
PRSI29-527
Beschreibung:
HNRPA3 plays a role in cytoplasmic trafficking of RNA. It binds to the cis-acting response element (A2RE) and may be involved in pre-mRNA splicing
VE:
1 * 100 µG
Lieferant:
CHEMPUR
Beschreibung:
2-Chlor-6-fluorzimtsäure
Lieferant:
Portwest Clothing
Beschreibung:
Stulpenhandschuh aus Nitril mit sandiger Handfläche für sicheren Griff und Abriebfestigkeit. Dieser Handschuh ist für den Einsatz in nassen und öligen Umgebungen konzipiert. Durch die Verwendung eines leichten, weichen, bequemen Futters wird der Tragekomfort über einen längeren Zeitraum erhöht.
Artikel-Nr:
(SIALC31600-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
C31600-25G
Lokale Artikelnummer::
SIALC31600-25G
Beschreibung:
4-Chlorzimtsäure, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
MP Biomedicals
Beschreibung:
Methylpalmitoleat, Flüssigkeit
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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