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4-Fluoro-1H-pyrazole
Artikel-Nr:
(BOSSBS-13202R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-FITC
Lokale Artikelnummer::
BOSSBS-13202R-FITC
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13202R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13202R-A555
Lokale Artikelnummer::
BOSSBS-13202R-A555
Beschreibung:
Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß and activin, indicating that these FAST proteins mediate TFGß induced signal transduction (3).
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
2-Amino-4,6-dichlorphenol
Artikel-Nr:
(1768.1000)
Lieferant:
Avantor
Lokale Artikelnummer::
BAKR1768.1000
Beschreibung:
Natriumdihydrogenphosphat Dihydrat, BAKER, Laborreagens, J.T.Baker®
VE:
1 * 1 kg
Lieferant:
VICI JOUR RESEARCH
Beschreibung:
Mit Flachfilterelement, das eine Entnahme der maximalen Menge an mobiler Phase aus dem Reservoir ermöglicht, ohne dass Luft in das System gelangt.
Artikel-Nr:
(ICNA0215250605)
Lieferant:
MP Biomedicals
Hersteller-Artikelnummer::
0215250605
Lokale Artikelnummer::
ICNA0215250605
Beschreibung:
Bromophenol blue is a tracking dye for alkaline and neutral buffer systems. It is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) gel electrophoresis.
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-12883R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12883R-A350
Lokale Artikelnummer::
BOSSBS-12883R-A350
Beschreibung:
The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9617R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9617R-HRP
Lokale Artikelnummer::
BOSSBS-9617R-HRP
Beschreibung:
C14orf174, is a 674 amino acid protein that contains one SAM (sterile alpha motif) domain. Existing as two alternatively spliced isoforms,C14orf174 is encoded by a gene that maps to human chromosome 14q24.3. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein Bcl-3 in the (14;19) translocations found in a variety of B cell malignancies.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9615R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9615R-A555
Lokale Artikelnummer::
BOSSBS-9615R-A555
Beschreibung:
C14orf106 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. It interacts with SP1. There are two isoforms.Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. The C14orf106 gene product has been provisionally designated C14orf106 pending further characterization.
VE:
1 * 100 µl
Lieferant:
Retsch GmbH
Beschreibung:
These grinding jars help to provide efficient milling.
Lieferant:
MACHEREY-NAGEL
Beschreibung:
Silica gel adsorbents for column chromatography.
Artikel-Nr:
(MOLE23253991-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
23253991-1KG
Lokale Artikelnummer::
MOLE23253991-1KG
Beschreibung:
Triphenylphosphin
VE:
1 * 1 kg
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(SIAL192546-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
192546-25G
Lokale Artikelnummer::
SIAL192546-25G
Beschreibung:
1,3-Dichlor-5-iodbenzol, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
Honeywell Chemicals
Beschreibung:
ACS GENERAL USE SOLVENTS
Lieferant:
Alfa Aesar
Beschreibung:
(±)-4-(Trifluormethyl)mandelsäure ≥98%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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