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Acetonitril:Methanol:2-Propanol:Wasser
Artikel-Nr:
(BOSSBS-1163R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1163R-FITC
Lokale Artikelnummer::
BOSSBS-1163R-FITC
Beschreibung:
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13475R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13475R-CY3
Lokale Artikelnummer::
BOSSBS-13475R-CY3
Beschreibung:
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0039R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0039R-CY5.5
Lokale Artikelnummer::
BOSSBS-0039R-CY5.5
Beschreibung:
The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4252R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4252R-CY5
Lokale Artikelnummer::
BOSSBS-4252R-CY5
Beschreibung:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7859R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7859R
Lokale Artikelnummer::
BOSSBS-7859R
Beschreibung:
3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. May play a role in the biosynthesis of retinoic acid from retinaldehyde, but seems to have low activity with retinoids. Can utilize both NADH and NADPH.Tissue specificity:Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5701R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5701R-A750
Lokale Artikelnummer::
BOSSBS-5701R-A750
Beschreibung:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5702R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5702R-A750
Lokale Artikelnummer::
BOSSBS-5702R-A750
Beschreibung:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4252R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4252R-A647
Lokale Artikelnummer::
BOSSBS-4252R-A647
Beschreibung:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5702R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5702R-A488
Lokale Artikelnummer::
BOSSBS-5702R-A488
Beschreibung:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11997R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11997R-CY5
Lokale Artikelnummer::
BOSSBS-11997R-CY5
Beschreibung:
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8586R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8586R-A488
Lokale Artikelnummer::
BOSSBS-8586R-A488
Beschreibung:
GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1226R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1226R-FITC
Lokale Artikelnummer::
BOSSBS-1226R-FITC
Beschreibung:
The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319 amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213 amino acid extracellular region, a single transmembrane domain, and a 62 amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11043R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11043R-CY5
Lokale Artikelnummer::
BOSSBS-11043R-CY5
Beschreibung:
Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11754R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11754R-CY5
Lokale Artikelnummer::
BOSSBS-11754R-CY5
Beschreibung:
SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11754R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11754R-CY7
Lokale Artikelnummer::
BOSSBS-11754R-CY7
Beschreibung:
SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6259R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6259R-A647
Lokale Artikelnummer::
BOSSBS-6259R-A647
Beschreibung:
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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