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N-Boc-D-serine+methyl+ester
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N-Boc-D-serine+methyl+ester
Artikel-Nr:
(BOSSBS-1427R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1427R-HRP
Lokale Artikelnummer::
BOSSBS-1427R-HRP
Beschreibung:
IRAK or Interleukin-1 Receptor-associated Kinase 1, is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This protein is partially responsible for IL1-induced upregulation of the ubiquitous transcription factor NF-kappa B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10339R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10339R-A680
Lokale Artikelnummer::
BOSSBS-10339R-A680
Beschreibung:
The complement pathway is an important host defense system that contributes to both innate and acquired immunity. There are three pathways of complement activation: the classical pathway, lectin pathway and alternative pathway. Complement protein Factor I is a key serine protease that modulates the complement cascade by regulating the levels of C3 convertases. It circulates in plasma as a heavily N-glycosylated heterodimer made up of two disulfide linked chains, each carrying three N-linked oligosaccharide chains that may have both structural and functional roles in the interactions with the natural substrate and the cofactor during catalysis. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement proteins; Factor H, CR1 or MCP are required for C3b cleavage, and C4bp or CR1 are required for C4b cleavage.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6411R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6411R-A488
Lokale Artikelnummer::
BOSSBS-6411R-A488
Beschreibung:
CDK5 (Cyclin Dependent Kinase 5) is serine/threonine kinase involved in synaptic regulation and neuronal development; phosphorylates synaptic protein Pctaire1; regulates acetylcholine receptor expression. CDK5 is a member of the cyclindependent kinase family of serine/threonine kinases. It is present in numerous mammalian tissues including kidney, testes, and ovary. Its activity is detected almost exclusively in brain extracts. Neuronal and muscle cells contain the highest amount of this protein. Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, the p35 protein, which is expressed solely in the brain, activates Cdk5. Cdk5 interacts with D1 and D3 type G1 cyclins and can phosphorylate histone H1, TAU, MAP2 and NF-H and NF-M. Cdk5 activity is involved in terminal differentiation of neurons and muscle cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11317R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A350
Lokale Artikelnummer::
BOSSBS-11317R-A350
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11317R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A750
Lokale Artikelnummer::
BOSSBS-11317R-A750
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11317R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11317R-A647
Lokale Artikelnummer::
BOSSBS-11317R-A647
Beschreibung:
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7557R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7557R-HRP
Lokale Artikelnummer::
BOSSBS-7557R-HRP
Beschreibung:
IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15088R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15088R-CY7
Lokale Artikelnummer::
BOSSBS-15088R-CY7
Beschreibung:
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9048R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9048R
Lokale Artikelnummer::
BOSSBS-9048R
Beschreibung:
TRPM6 is an essential ion channel and serine/threonine-protein kinase, and is crucial for magnesium homeostasis. TRPM6 also has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney. The various isoforms of the type M6-kinase lack the ion channel region.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0731R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0731R-CY7
Lokale Artikelnummer::
BOSSBS-0731R-CY7
Beschreibung:
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7557R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7557R-A750
Lokale Artikelnummer::
BOSSBS-7557R-A750
Beschreibung:
IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7557R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7557R-A555
Lokale Artikelnummer::
BOSSBS-7557R-A555
Beschreibung:
IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7557R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7557R-FITC
Lokale Artikelnummer::
BOSSBS-7557R-FITC
Beschreibung:
IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7850R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7850R-A350
Lokale Artikelnummer::
BOSSBS-7850R-A350
Beschreibung:
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2775R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2775R-CY3
Lokale Artikelnummer::
BOSSBS-2775R-CY3
Beschreibung:
Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop. LIMK1 subsequently phosphorylates and inactivates the actin binding/depolymerizing factors cofilin-1/CFL1, cofilin-2/CFL2 and destrin/DSTN, thereby preventing the cleavage of filamentous actin (F-actin), and stabilizing the actin cytoskeleton. In this way LIMK1 regulates several actin-dependent biological processes including cell motility, cell cycle progression, and differentiation. Phosphorylates TPPP on serine residues, thereby promoting microtubule disassembly. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. Required for atypical chemokine receptor ACKR2-induced phosphorylation of cofilin (CFL1).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2775R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2775R-CY5
Lokale Artikelnummer::
BOSSBS-2775R-CY5
Beschreibung:
Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop. LIMK1 subsequently phosphorylates and inactivates the actin binding/depolymerizing factors cofilin-1/CFL1, cofilin-2/CFL2 and destrin/DSTN, thereby preventing the cleavage of filamentous actin (F-actin), and stabilizing the actin cytoskeleton. In this way LIMK1 regulates several actin-dependent biological processes including cell motility, cell cycle progression, and differentiation. Phosphorylates TPPP on serine residues, thereby promoting microtubule disassembly. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. Required for atypical chemokine receptor ACKR2-induced phosphorylation of cofilin (CFL1).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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