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Adapter,+Gewinderohre
Artikel-Nr:
(BOSSBS-1460R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1460R-A555
Lokale Artikelnummer::
BOSSBS-1460R-A555
Beschreibung:
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9790R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9790R-A680
Lokale Artikelnummer::
BOSSBS-9790R-A680
Beschreibung:
Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2885R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2885R-FITC
Lokale Artikelnummer::
BOSSBS-2885R-FITC
Beschreibung:
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2941R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2941R-CY7
Lokale Artikelnummer::
BOSSBS-2941R-CY7
Beschreibung:
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2941R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2941R-CY3
Lokale Artikelnummer::
BOSSBS-2941R-CY3
Beschreibung:
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4071R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4071R-CY5.5
Lokale Artikelnummer::
BOSSBS-4071R-CY5.5
Beschreibung:
Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3157R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3157R
Lokale Artikelnummer::
BOSSBS-3157R
Beschreibung:
GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6855R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6855R-FITC
Lokale Artikelnummer::
BOSSBS-6855R-FITC
Beschreibung:
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2104R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2104R-CY5.5
Lokale Artikelnummer::
BOSSBS-2104R-CY5.5
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8048R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8048R-CY5
Lokale Artikelnummer::
BOSSBS-8048R-CY5
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
VE:
1 * 100 µl
Artikel-Nr:
(111-1883)
Lieferant:
UVEX
Hersteller-Artikelnummer::
9924.010
Lokale Artikelnummer::
UVEX9924.010
Beschreibung:
Dieses Helmvisier aus robustem Polycarbonat schützt vor den Auswirkungen von elektrischen Lichtbögen. Es ist kompatibel mit uvex Schutzhelmen und dem uvex 2H, uvex 3H und uvex 3200H Gehörschutz mit Helmmontage.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-2921R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2921R-A750
Lokale Artikelnummer::
BOSSBS-2921R-A750
Beschreibung:
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
VE:
1 * 100 µl
Lieferant:
BURKLE
Beschreibung:
Das ausziehbare Steigrohr passt sich beim Einsetzen der Handpumpe an die Behälterhöhe an. Dadurch ist eine gute Restentleerung gewährleistet und die Handpumpe kann für verschiedene Behälter verwendet werden.
Artikel-Nr:
(40-5874-U500)
Lieferant:
Tonbo Biosciences
Hersteller-Artikelnummer::
40-5874-U500
Lokale Artikelnummer::
TNBO40-5874-U500
Beschreibung:
The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.
VE:
1 * 500 µG
Lieferant:
Lenz Laborglas GmbH & CO.KG
Beschreibung:
DURAN®, Borosilikatglas, klar.
Artikel-Nr:
(BOSSBS-2104R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2104R-HRP
Lokale Artikelnummer::
BOSSBS-2104R-HRP
Beschreibung:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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