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Adapter,+Gewinderohre
Artikel-Nr:
(300-1044)
Lieferant:
BURKLE
Hersteller-Artikelnummer::
5314-3000
Lokale Artikelnummer::
BURK5314-3000
Beschreibung:
Glasflasche und Schlauch sind elektrisch leitend verbunden und werden über ein Massekabel geerdet. Einfache Handhabung: Gerät erden, Saugschlauch in gewünschte Tiefe absenken, Adapter auf Probenflasche aufstecken, mit Handpumpe Vakuum erzeugen, Probe sammeln, befüllte Probenflasche abnehmen, verschließen und etikettieren.
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-5550R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5550R-A680
Lokale Artikelnummer::
BOSSBS-5550R-A680
Beschreibung:
Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11702R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11702R-A350
Lokale Artikelnummer::
BOSSBS-11702R-A350
Beschreibung:
The endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the endophilins are consistent with their cellular functions at the neuronal synapse, as Endophilin I is ex- pressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G protein-coupled receptor signaling by functioning as an adapter protein and directing 1 adrenergic receptors to the endocytic machinery.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2921R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2921R-A555
Lokale Artikelnummer::
BOSSBS-2921R-A555
Beschreibung:
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3003R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3003R
Lokale Artikelnummer::
BOSSBS-3003R
Beschreibung:
APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adaptor protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganisation. A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2731R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2731R
Lokale Artikelnummer::
BOSSBS-2731R
Beschreibung:
APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adaptor protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganisation. A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3657R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3657R
Lokale Artikelnummer::
BOSSBS-3657R
Beschreibung:
FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity.Studies of FLASH protein suggested that this protein may be a component of the death inducing signaling complex that includes Fas receptor, Fas binding adapter FADD, and caspase 8, and plays a regulatory role in Fas mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8541R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8541R-CY7
Lokale Artikelnummer::
BOSSBS-8541R-CY7
Beschreibung:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
VE:
1 * 100 µl
Lieferant:
Pall Laboratory
Beschreibung:
Filter holder, Vakuumport-Adapter, SolVac®
Artikel-Nr:
(BOSSBS-8541R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8541R-A350
Lokale Artikelnummer::
BOSSBS-8541R-A350
Beschreibung:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8541R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8541R-A647
Lokale Artikelnummer::
BOSSBS-8541R-A647
Beschreibung:
C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9628R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9628R
Lokale Artikelnummer::
BOSSBS-9628R
Beschreibung:
C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1820R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1820R-A647
Lokale Artikelnummer::
BOSSBS-1820R-A647
Beschreibung:
High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9628R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9628R-CY5
Lokale Artikelnummer::
BOSSBS-9628R-CY5
Beschreibung:
C16orf44 is a 616 amino acid protein that contains six Kelch repeats, one BTB/POZ domain and one BTB/Kelch associated (BACK) domain. C16orf44 is believed to play a role in protein ubiquitination and may function as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, C16orf44 interacts with CUL-3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin-mediated proteolysis. Due to alternative splicing events, two isoforms of C16orf44 are expressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1330R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1330R-CY5
Lokale Artikelnummer::
BOSSBS-1330R-CY5
Beschreibung:
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1330R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1330R-CY7
Lokale Artikelnummer::
BOSSBS-1330R-CY7
Beschreibung:
Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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