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Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
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Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
Artikel-Nr:
(BOSSBS-2139R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2139R-FITC
Lokale Artikelnummer::
BOSSBS-2139R-FITC
Beschreibung:
L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13518R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13518R-FITC
Lokale Artikelnummer::
BOSSBS-13518R-FITC
Beschreibung:
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1325R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1325R-A680
Lokale Artikelnummer::
BOSSBS-1325R-A680
Beschreibung:
Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.
VE:
1 * 100 µl
Lieferant:
Bernd Kraft
Beschreibung:
di-Kaliumoxalat Monohydrat, reinst
Artikel-Nr:
(BOSSBS-2167R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2167R-CY5.5
Lokale Artikelnummer::
BOSSBS-2167R-CY5.5
Beschreibung:
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing). Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2) and serotonin (HTR2C) and GABA receptor (GABRA3). Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alters their functional activities. Exhibits low-level editing at the GRIA2 Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Its viral RNA substrates include: hepatitis C virus (HCV), vesicular stomatitis virus (VSV), measles virus (MV), hepatitis delta virus (HDV), and human immunodeficiency virus type 1 (HIV-1). Exhibits either a proviral (HDV, MV, VSV and HIV-1) or an antiviral effect (HCV) and this can be editing-dependent (HDV and HCV), editing-independent (VSV and MV) or both (HIV-1). Impairs HCV replication via RNA editing at multiple sites. Enhances the replication of MV, VSV and HIV-1 through an editing-independent mechanism via suppression of EIF2AK2/PKR activation and function. Stimulates both the release and infectivity of HIV-1 viral particles by an editing-dependent mechanism where it associates with viral RNAs and edits adenosines in the 5'UTR and the Rev and Tat coding sequence.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Calciumacetat Monohydrat ACS
Artikel-Nr:
(BOSSBS-7344R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7344R-A350
Lokale Artikelnummer::
BOSSBS-7344R-A350
Beschreibung:
The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13077R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13077R-A680
Lokale Artikelnummer::
BOSSBS-13077R-A680
Beschreibung:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13077R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13077R
Lokale Artikelnummer::
BOSSBS-13077R
Beschreibung:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(MOLE28352631-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
28352631-25G
Lokale Artikelnummer::
MOLE28352631-25G
Beschreibung:
1,10-Phenanthrolin Hydrochlorid Monohydrat
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
Sigma-Aldrich
Beschreibung:
1,10-Phenanthrolin Monohydrat, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
2-Amino-2-methylpropanol, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
L(+)-Lysin Monohydrat, Sigma-Aldrich®
Lieferant:
Thermo Scientific
Beschreibung:
Mangan(II)sulfat Monohydrat 98+% ACS
Artikel-Nr:
(MOLE21508672-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
21508672-1KG
Lokale Artikelnummer::
MOLE21508672-1KG
Beschreibung:
tri-Kaliumcitrat Monohydrat
VE:
1 * 1 kg
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(MOLE35827584-100G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
35827584-100G
Lokale Artikelnummer::
MOLE35827584-100G
Beschreibung:
5-Amino-1H-tetrazol Monohydrat
VE:
1 * 100 g
This is a MarketSource item. Additional charges may apply
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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