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Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
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Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
Artikel-Nr:
(116802-10)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
116802-10
Lokale Artikelnummer::
CALB116802-10
Beschreibung:
A potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
VE:
1 * 10 µmol
Artikel-Nr:
(BOSSBS-6526R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6526R-CY3
Lokale Artikelnummer::
BOSSBS-6526R-CY3
Beschreibung:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP >IDP >UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6526R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6526R-CY7
Lokale Artikelnummer::
BOSSBS-6526R-CY7
Beschreibung:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP >IDP >UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13077R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13077R-A647
Lokale Artikelnummer::
BOSSBS-13077R-A647
Beschreibung:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7344R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7344R-A350
Lokale Artikelnummer::
BOSSBS-7344R-A350
Beschreibung:
The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4913R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4913R-A680
Lokale Artikelnummer::
BOSSBS-4913R-A680
Beschreibung:
By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyses ATP, but can also hydrolyse other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13077R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13077R-A680
Lokale Artikelnummer::
BOSSBS-13077R-A680
Beschreibung:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13077R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13077R
Lokale Artikelnummer::
BOSSBS-13077R
Beschreibung:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
2-Morpholinoethanesulfonic acid monohydrate (MES) is suitable for biopharmaceutical production EMPROVE® bio.
Lieferant:
Sigma-Aldrich
Beschreibung:
β-(N-Morpholino)ethansulfonsäure (MES) Monohydrat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-7344R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7344R-A647
Lokale Artikelnummer::
BOSSBS-7344R-A647
Beschreibung:
The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7344R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7344R-A750
Lokale Artikelnummer::
BOSSBS-7344R-A750
Beschreibung:
The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Mangan(II)chlorid Monohydrat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-13077R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13077R-CY7
Lokale Artikelnummer::
BOSSBS-13077R-CY7
Beschreibung:
Equilibrative nucleoside transporters (ENTs) regulate many physiological processes and are widely distributed in mammals, plants, yeasts, insects, nematodes and protozoans. They enable facilitated diffusion of hydrophilic nucleosides, such as adenosine and nucleoside analogs, across cell membranes. ENTs are required for uptake of antiviral and anticancer nucleoside drugs and influence a variety of physiological processes, such as neurotransmission and platelet aggregation, by regulating the amount of adenoside available to cell surface receptors. Equilibrative nucleoside transporter 1 (ENT1), also designated solute carrier family 29 (nucleoside transporters), member 1, belongs to the SLC29A transporter family and is a mammalian ENT isoform. ENT1, along with ENT3, mediates the majority of influx and efflux of nucleosides across the plasma membrane.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6760R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6760R-A555
Lokale Artikelnummer::
BOSSBS-6760R-A555
Beschreibung:
Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned KCNQ1/KCNE1 channels were coexpressed with M1 muscarinic receptors. May associate also with KCNE3 (MiRP2) to form the potassium channel that is important for cyclic AMP-stimulated intestinal secretion of chloride ions, which is reduced in cystic fibrosis and pathologically stimulated in cholera and other forms of secretory diarrhea.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8160R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8160R-CY5.5
Lokale Artikelnummer::
BOSSBS-8160R-CY5.5
Beschreibung:
GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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