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Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
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Adenosin-5'-monophosphorsäure+(AMP)+Monohydrat
Artikel-Nr:
(BOSSBS-13393R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13393R-A680
Lokale Artikelnummer::
BOSSBS-13393R-A680
Beschreibung:
Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12045R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12045R-A350
Lokale Artikelnummer::
BOSSBS-12045R-A350
Beschreibung:
Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12045R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12045R-HRP
Lokale Artikelnummer::
BOSSBS-12045R-HRP
Beschreibung:
Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11383R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11383R-A488
Lokale Artikelnummer::
BOSSBS-11383R-A488
Beschreibung:
ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.
VE:
1 * 100 µl
Artikel-Nr:
(SIALM7899-500G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
M7899-500G
Lokale Artikelnummer::
SIALM7899-500G
Beschreibung:
Mangan(II)sulfat Monohydrat, Sigma-Aldrich®
VE:
1 * 500 g
Lieferant:
MP Biomedicals
Beschreibung:
Storage: -20 °C.
Adenosine 5'-triphosphate (ATP) and its phosphate bonds are the basic components of energy exchange in many biological systems. Adenosine 5'-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is used in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions. P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems.
Artikel-Nr:
(BOSSBS-13507R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13507R-HRP
Lokale Artikelnummer::
BOSSBS-13507R-HRP
Beschreibung:
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2139R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2139R-FITC
Lokale Artikelnummer::
BOSSBS-2139R-FITC
Beschreibung:
L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13518R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13518R-FITC
Lokale Artikelnummer::
BOSSBS-13518R-FITC
Beschreibung:
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 128 (GPR128), a member of the secretin family of GCPRs with a GPS domain in its N-terminal domain, may mediate signaling processes to the interior of the cell via activation of G proteins. GPR128 represents an allopeptide which may be involved in T cell mediated transplant rejection as it is able to stimulate 2.102 T cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1325R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1325R-A680
Lokale Artikelnummer::
BOSSBS-1325R-A680
Beschreibung:
Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
tri-Kaliumcitrat Monohydrat 99,0-100,5% (durch Perchlorsäure-Titration), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, FCC, E332, SAFC®
Lieferant:
Merck
Beschreibung:
Citronensäure Monohydrat 99,5-100,5% (alkalimetrisch, berechnet an wasserfreien Substanzen), Pulver, EMPROVE® ESSENTIAL Ph. Eur., BP, JP, USP, E330, FCC, SAFC®
Lieferant:
MP Biomedicals
Beschreibung:
L-Lysine is an essential proteinogenic α amino acid. It contains an N-butyl amino group in the side chain, and this moiety is protonated at physiological pH. In addition, L-lysine is one of the two amino acids that are degraded to give ketone bodies (a ketogenic amino acid).
Artikel-Nr:
(MOLE26904615-1KG)
Lieferant:
Molekula
Hersteller-Artikelnummer::
26904615-1KG
Lokale Artikelnummer::
MOLE26904615-1KG
Beschreibung:
Betain Monohydrat
VE:
1 * 1 kg
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-3967R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3967R-CY7
Lokale Artikelnummer::
BOSSBS-3967R-CY7
Beschreibung:
PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Tetraphenylarsoniumchlorid Monohydrat, Sigma-Aldrich®
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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