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1-Acetylisonipecotoyl+chloride
Artikel-Nr:
(BOSSBS-7865R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7865R-CY5.5
Lokale Artikelnummer::
BOSSBS-7865R-CY5.5
Beschreibung:
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5777R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5777R-CY5
Lokale Artikelnummer::
BOSSBS-5777R-CY5
Beschreibung:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0572R-PE)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0572R-PE
Lokale Artikelnummer::
BOSSBS-0572R-PE
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7779R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7779R-CY3
Lokale Artikelnummer::
BOSSBS-7779R-CY3
Beschreibung:
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2162R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2162R-CY3
Lokale Artikelnummer::
BOSSBS-2162R-CY3
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6800R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6800R-CY5
Lokale Artikelnummer::
BOSSBS-6800R-CY5
Beschreibung:
Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2162R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2162R-CY5
Lokale Artikelnummer::
BOSSBS-2162R-CY5
Beschreibung:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7865R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7865R-CY5
Lokale Artikelnummer::
BOSSBS-7865R-CY5
Beschreibung:
Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
VE:
1 * 100 µl
Lieferant:
Tonbo Biosciences
Beschreibung:
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
Lieferant:
Tonbo Biosciences
Beschreibung:
The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.
Artikel-Nr:
(BOSSBS-3890R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3890R-A350
Lokale Artikelnummer::
BOSSBS-3890R-A350
Beschreibung:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2081R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2081R-HRP
Lokale Artikelnummer::
BOSSBS-2081R-HRP
Beschreibung:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a myeloid associated differentiation antigen in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell type in human tissues. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of human and monkey myeloid cells. This MAb is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.
Artikel-Nr:
(BOSSBS-2937R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2937R-A680
Lokale Artikelnummer::
BOSSBS-2937R-A680
Beschreibung:
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localises to the endoplasmic reticulum and the Golgi apparatus.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3890R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3890R-A680
Lokale Artikelnummer::
BOSSBS-3890R-A680
Beschreibung:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidised.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2081R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2081R-A350
Lokale Artikelnummer::
BOSSBS-2081R-A350
Beschreibung:
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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