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Aluminum+oxide-Silicon+oxide
Artikel-Nr:
(BOSSBS-0156R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0156R-A555
Lokale Artikelnummer::
BOSSBS-0156R-A555
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2072R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2072R-A680
Lokale Artikelnummer::
BOSSBS-2072R-A680
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7632R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7632R-FITC
Lokale Artikelnummer::
BOSSBS-7632R-FITC
Beschreibung:
This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2537R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2537R-A647
Lokale Artikelnummer::
BOSSBS-2537R-A647
Beschreibung:
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2537R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2537R-CY5
Lokale Artikelnummer::
BOSSBS-2537R-CY5
Beschreibung:
Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC and PCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose tissue. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11289R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11289R
Lokale Artikelnummer::
BOSSBS-11289R
Beschreibung:
Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5133R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5133R
Lokale Artikelnummer::
BOSSBS-5133R
Beschreibung:
ALDH1B1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. The ALDH1B1 gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0156R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0156R-HRP
Lokale Artikelnummer::
BOSSBS-0156R-HRP
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11987R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11987R-A488
Lokale Artikelnummer::
BOSSBS-11987R-A488
Beschreibung:
CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2920R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2920R
Lokale Artikelnummer::
BOSSBS-2920R
Beschreibung:
ECHS1(Enoyl Coenzyme A hydratase, short chain, 1) catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs, in the second step of the mitochondrial fatty acid beta-oxidation pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8259R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R-CY5
Lokale Artikelnummer::
BOSSBS-8259R-CY5
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8259R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8259R
Lokale Artikelnummer::
BOSSBS-8259R
Beschreibung:
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Yttrium(III)acetylacetonat Hydrat ≥99,9% (REO, Basis der Oxide der Metalle der seltenen Erden)
Artikel-Nr:
(BOSSBS-2072R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2072R-CY5.5
Lokale Artikelnummer::
BOSSBS-2072R-CY5.5
Beschreibung:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12461R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12461R-CY3
Lokale Artikelnummer::
BOSSBS-12461R-CY3
Beschreibung:
Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9634R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9634R-CY5.5
Lokale Artikelnummer::
BOSSBS-9634R-CY5.5
Beschreibung:
The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ?ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ?ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Ca2+ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg2+. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock. IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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