(4-Chlor-2-fluorphenyl)essigsäure
Artikel-Nr:
(BOSSBS-3831R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3831R-A555
Lokale Artikelnummer::
BOSSBS-3831R-A555
Beschreibung:
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15483R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15483R
Lokale Artikelnummer::
BOSSBS-15483R
Beschreibung:
HIBADH is a 336 amino acid mitochondrial enzyme that catalyzes the NAD+-dependent, reversible oxidization of 3-Hydroxyisobutyrate to methylmalonate semialdehyde, an intermediate of valine catabolism. The enzyme functions as a homodimer between a pH of 7.0 and 10.0, with optimal activity between 8.8 and 9.0. It was previously hypothesized that defects in the gene encoding HIBADH may be the cause of 3-Hydroxyisobutyric aciduria, a rare disorder that is characterized by a variety of clinical manifestations such as neurodevelopmental problems and dysmorphic features. However, it was shown that HIBADH activity was equal in patients with 3-Hydroxyisobutyric aciduria as compared with controls.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5045R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5045R-CY5
Lokale Artikelnummer::
BOSSBS-5045R-CY5
Beschreibung:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Tritolylphosphat (Isomerengemisch) ≥98% ortho-isomers <1%
Artikel-Nr:
(BOSSBS-3892R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3892R-CY7
Lokale Artikelnummer::
BOSSBS-3892R-CY7
Beschreibung:
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Titan(IV)oxid, Aeroxide® P25
Artikel-Nr:
(HONE12236.9050)
Lieferant:
Honeywell Chemicals
Hersteller-Artikelnummer::
12236.9050
Lokale Artikelnummer::
HONE12236.9050
Beschreibung:
Chrom(VI)oxid
VE:
1 * 50 kg
Lieferant:
COMBI-BLOCKS
Beschreibung:
4-Nitro-2-picolin-N-oxid
Artikel-Nr:
(ENAMEN300105768.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN300105768.1G
Lokale Artikelnummer::
ENAMEN300105768.1G
Beschreibung:
4-Nitro-2-picolin-N-oxid
VE:
1 * 1 g
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Artikel-Nr:
(BOSSBS-20297R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-20297R-A680
Lokale Artikelnummer::
BOSSBS-20297R-A680
Beschreibung:
Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11279R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11279R-A350
Lokale Artikelnummer::
BOSSBS-11279R-A350
Beschreibung:
ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3892R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3892R-A555
Lokale Artikelnummer::
BOSSBS-3892R-A555
Beschreibung:
Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11279R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11279R-FITC
Lokale Artikelnummer::
BOSSBS-11279R-FITC
Beschreibung:
ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11279R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11279R-A647
Lokale Artikelnummer::
BOSSBS-11279R-A647
Beschreibung:
ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3614R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3614R-CY3
Lokale Artikelnummer::
BOSSBS-3614R-CY3
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13048R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13048R-CY5
Lokale Artikelnummer::
BOSSBS-13048R-CY5
Beschreibung:
ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
VE:
1 * 100 µl
Preis auf Anfrage
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