Aluminum+oxide-Silicon+oxide
Artikel-Nr:
(SIAL555657-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
555657-25G
Lokale Artikelnummer::
SIAL555657-25G
Beschreibung:
3,5-Lutidin-N-oxid, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
Sigma-Aldrich
Beschreibung:
Chrom(III)oxid, Sigma-Aldrich®
Artikel-Nr:
(ABCRAB111934.0500)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB111934.0500
Lokale Artikelnummer::
ABCRAB111934.0500
Beschreibung:
Yttrium(III)oxid ≥99,9% (Y-Basis)
VE:
1 * 500 g
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Lieferant:
Merck
Beschreibung:
Anaerocult® ist ein sicheres und bewährtes System zur Kultivierung anaerober und mikroaerophiler Mikroorganismen. Zum Anaerocult®- System gehören Reagenzbeutel in verschiedenen Größen, die mit einer sauerstoffbindenden und kohlendioxiderzeugenden Reagenzmischung gefüllt sind. Die Reaktion wird durch Hinzufügen von Wasser ausgelöst. Sie besteht in der Oxidation von fein verteiltem Eisen und findet ohne Katalysator statt. Das Anaerocult®-System besteht aus verschiedenen Inkubationsmöglichkeiten.
Artikel-Nr:
(BOSSBS-4903R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4903R
Lokale Artikelnummer::
BOSSBS-4903R
Beschreibung:
SLC27A1 (Solute carrier family 27 member 1) is involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. SLC27A1 may act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. It also plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis and may be involved in regulation of cholesterol metabolism.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-20297R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-20297R-A750
Lokale Artikelnummer::
BOSSBS-20297R-A750
Beschreibung:
Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2578R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2578R-FITC
Lokale Artikelnummer::
BOSSBS-2578R-FITC
Beschreibung:
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-A350
Lokale Artikelnummer::
BOSSBS-5983R-A350
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11279R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11279R-A555
Lokale Artikelnummer::
BOSSBS-11279R-A555
Beschreibung:
ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3614R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3614R-A488
Lokale Artikelnummer::
BOSSBS-3614R-A488
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4055R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4055R-A350
Lokale Artikelnummer::
BOSSBS-4055R-A350
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4055R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4055R-CY3
Lokale Artikelnummer::
BOSSBS-4055R-CY3
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13048R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13048R-CY7
Lokale Artikelnummer::
BOSSBS-13048R-CY7
Beschreibung:
ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4055R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4055R-HRP
Lokale Artikelnummer::
BOSSBS-4055R-HRP
Beschreibung:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11667R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11667R-A647
Lokale Artikelnummer::
BOSSBS-11667R-A647
Beschreibung:
PET112L is the human homolog of the S. cerevisiae COX assembly protein pet112, a protein that is believed to play an important role in the translation of mitochondrial genes. PET112L, also known as HSPC199 or Glu-ADT subunit B (glutamyl-tRNA(Gln) amidotransferase subunit B), is a 557 amino acid protein belonging to the gatB/gatE family of proteins (GatB subfamily) and is believed to play a role in energy metabolism. Localizing to mitochondria, PET112L is expressed in tissues such as heart and muscle, which exhibit high rates of oxidative phosphorylation. The gene encoding PET112L is overexpressed in recurrent ependymoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5150R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5150R-CY7
Lokale Artikelnummer::
BOSSBS-5150R-CY7
Beschreibung:
Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Does also incise at AP sites in the DNA strand of DNA/RNA hybrids, single-stranded DNA regions of R-loop structures, and single-stranded RNA molecules. Has a 3'-5' exoribonuclease activity on mismatched deoxyribonucleotides at the 3' termini of nicked or gapped DNA molecules during short-patch BER. Possesses a DNA 3' phosphodiesterase activity capable of removing lesions (such as phosphoglycolate) blocking the 3' side of DNA strand breaks. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. Acts as a loading factor for POLB onto non-incised AP sites in DNA and stimulates the 5'-terminal deoxyribose 5'-phosphate (dRp) excision activity of POLB. Plays a role in the protection from granzymes-mediated cellular repair leading to cell death. Also involved in the DNA cleavage step of class switch recombination (CSR). On the other hand, APEX1 also exerts reversible nuclear redox activity to regulate DNA binding affinity and transcriptional activity of transcriptional factors by controlling the redox status of their DNA-binding domain, such as the FOS/JUN AP-1 complex after exposure to IR. Involved in calcium-dependent down-regulation of parathyroid hormone (PTH) expression by binding to negative calcium response elements (nCaREs).
VE:
1 * 100 µl
Preis auf Anfrage
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